Myrrhanol A
Posted by naturalproductman on July 6, 2009
Alejandro Barrero at the University of Granada in Spain and co-workers have recently published in JOC on the synthesis of an anti-inflammatory agent, myrrhanol A. A key step in the synthesis was the reaction they used to make the 6,6-scaffold of the molecule, which involved a cascade titanium mediated bis-olefin epoxide opening cyclization.
Edinburgher said
Hey man, Barrero didnt set up the whole Uni and then name it after himself.
Furthermore, there is a long tradition of Ti(III)-chemistry in that Uni with titanocenes, some of it really interesting. In particular there is an Angewandte of 2006 (as far as I remember), quite cool.
naturalproductman said
Woops thanks for the correction! And thanks for the reference.