Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for September, 2011

Acortatarins syntheses

Posted by naturalproductman on September 30, 2011

Gangarajula Sudhakar and co-workers at IICT have reported in Organic Letters on the synthesis of acortatarins.

acortatarins

OL paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Methodology, Spirocycles, Spiroketals, Total Synthesis | Leave a Comment »

Organocatalytic oxy-Michael

Posted by naturalproductman on September 30, 2011

Seirjiro Matsubara and colleague at Kyoto University have reported in JACS on an organocatalytic oxy-Michael reaction.

intramolecular

JACS paper

Posted in Asymmetric, Conjugate Additions, Methodology, Michael, Named Reactions, Organocatalytic | Leave a Comment »

Cycloheptenes using PIFA

Posted by naturalproductman on September 28, 2011

Siegfried Waldvogel and co-workers at the University of Bonn have reported in European JOC on a hypervalent iodine mediated cyclization.

PIFA

European JOC paper

Posted in Cascade Reactions, Hypervalent Iodine, Methodology, Seven-Membered Rings | 1 Comment »

Aspergillide synthesis

Posted by naturalproductman on September 28, 2011

Srihari and colleague at IICT have reported in European JOC on the syntheses of aspergillide.

aspergillide

European JOC paper

Posted in Achmatowicz rearrangement, Asymmetric, Ferrier, Macrolides, Methodology, Named Reactions | Leave a Comment »

Intramolecular [2+2]

Posted by naturalproductman on September 28, 2011

Thorsten Bach and colleagues have reported in JACS on an intramolecular [2+2] photocycloaddition.

photocycloaddition

JACS paper

Posted in Cascade Reactions, Cycloaddition, Light Mediated, Methodology, Pericyclic reactions, [2+2] | Leave a Comment »

Aplyronine A-biotin derivative

Posted by naturalproductman on September 28, 2011

Hideo Kogoshi and co-workers at the University of Tsukuba have reported in ACIEE on an aplyronine A probe that is biotinylated.

probe

ACIEE paper

Posted in Chemical Biology, Macrolides, Methodology | Leave a Comment »

MCC with Sonogashira

Posted by naturalproductman on September 28, 2011

Matthius Beller and co-workers at Universitat Rostock
Albert-Einstein-Strasse have reported in ACIEE on a palladium catalyzed carbonylative Sonogashira coupling.

palladium

ACIEE paper

Posted in Cascade Reactions, cross coupling, Methodology, Palladium, Sonogashira, Transition Metal | Leave a Comment »

Fluoride displacement via Sn2 prime

Posted by naturalproductman on September 28, 2011

Jean-Francois Paquin and co-workers from the Universite Laval have reported in ACIEE on an Sn2 prime displacement of a fluoride group starting with an allylic bis-fluoride substrate to afford a vinyl fluoride.

sn2 prime

ACIEE paper

Posted in Cascade Reactions, Methodology, Sn2 prime | Leave a Comment »

Nickel catalyzed double C-H activation

Posted by naturalproductman on September 28, 2011

Janis Louie and colleague have reported in ACIEE on a nickel catalyzed double C-H activation reaction.

C-H

ACIEE paper

Posted in C-H activation, Methodology, Nickel, Transition Metal | Leave a Comment »

Aminohydroxylation of alkenes

Posted by naturalproductman on September 28, 2011

Timothy Donohoe and co-workers at the University of Oxford have reported in ACIEE on an intermolecular aminohydroxylation reaction of alkenes using an osmium catalyst.

aminohydroxylation

ACIEE paper

Posted in Cascade Reactions, Methodology, Osmium, Transition Metal | Leave a Comment »

 
Follow

Get every new post delivered to your Inbox.

Join 68 other followers