Naturalproductman’s Blog

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Archive for June, 2012

Myxalamide synthesis

Posted by naturalproductman on June 21, 2012

Susumu Kobayashi and co-workers at the Tokyo University of Science have reported in ACIE on the synthesis of myxalamide.

myxalamide

ACIE paper

Posted in Alkaloids, cross coupling, Methodology, Polyenes | Leave a Comment »

Fusarisetin A synthesis

Posted by naturalproductman on June 21, 2012

Shuanhu Gao and co-workers at East China Normal University have reported in ACIE on the synthesis of fusarisetin through an intramolecular Diels-Alder in addition to an interesting manganese catalyzed radical cyclization to form an endoperoxide that is transformed to the tetrahydrofuran ring.

fusarisetin

ACIE paper

Posted in Alkaloids, Cascade Reactions, Manganese, Methodology, Radical Chemistry, Transition Metal | Leave a Comment »

Silver catalyzed decarboxylative fluorination

Posted by naturalproductman on June 14, 2012

Chaozhong Li and co-workers at Shanghai Institute of Organic Chemistry have reported in JACS on a silver catalyzed decarboxylative fluorination.

decarboxylative fluorination

JACS paper

Posted in Cascade Reactions, Methodology, Silver, Transition Metal | 3 Comments »

Madindoline from desymmetrization

Posted by naturalproductman on June 13, 2012

Koichi Mikami and co-workers from Tokyo Institute of Technology have reported in JACS on a desymmetrization approach to access madindoline B.

desymmetrization

JACS paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Copper, Desymmetrization, Methodology, Transition Metal | Leave a Comment »

A Heck reaction for a seven membered ring

Posted by naturalproductman on June 11, 2012

Silas Cook and colleague at Indiana University have reported in Organic Letters on a formal synthesis of englerin.
englerin

OL paper

Posted in cross coupling, Heck, Methodology, Sesquiterpenoids, Seven-Membered Rings | Leave a Comment »

RIP Zimmerman

Posted by naturalproductman on June 6, 2012

I didn’t know that Howard Zimmerman died – yup the Zimmerman-Traxler Zimmerman.

ACIE paper

Posted in Random | Leave a Comment »

 
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