Hironao Sajiki and co-workers from Gifu Pharmaceutical University have reported in ACIE on a generation of naphthoquinone methides using an iron catalyst.
Archive for December, 2012
Complanadines A and B syntheses
Posted by naturalproductman on December 29, 2012
Masahiro Hirama and colleagues at Tohoku University have reported in ACIE on the syntheses of complanadines A and B.

Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »
Kingianin A synthesis
Posted by naturalproductman on December 29, 2012
Kathlyn Parker and colleague from Stony Brook University have reported in Organic Letters on the synthesis of kingianin A.

Posted in Amides, Total Synthesis | Leave a Comment »
Fluevirosines A-C
Posted by naturalproductman on December 29, 2012
Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in OL on the isolation of fluevirosines A-C.

Posted in Alkaloids | Leave a Comment »
Siladenoserinols
Posted by naturalproductman on December 29, 2012
Sachiko Tsukamoto and co-workers from Kumamoto University have reported in Organic Letters on the isolation of siladenoserinols A-L, which had inhibitory activity against p53 and HDM2 interaction.

Posted in Cancer, p53, Protein Targets | Leave a Comment »
Nahuoic acid A
Posted by naturalproductman on December 29, 2012
Raymond Andersen and co-workers from the University of British Columbia have reported in Organic Letters on the isolation of nahuoic acid A.

Posted in Histone-lysine N-methyltransferase SETD8, Polyketides, Protein Targets | Leave a Comment »
Methyl sarcotroates
Posted by naturalproductman on December 29, 2012
Yue-Wei Guo and co-workers at the Chinese Academy of Sciences have reported in Organic Letters on the isolation of some diterpenoids.

Posted in Diterpenoids, Protein Targets, protein tyrosine phosphatase 1B (PTP1B) | Leave a Comment »
Full report on scholarisine A
Posted by naturalproductman on December 29, 2012
Posted in Alkaloids, Total Synthesis | Leave a Comment »



