Naturalproductman’s Blog

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Archive for January, 2013

Pulchranin A

Posted by naturalproductman on January 31, 2013

Tatyana Makarieva and co-workers from the Russian Academy of Sciences have reported in Tetrahedron Letters on the isolation of pulchranin A.

pulchranin A

TL paper

Posted in Alkaloids | Leave a Comment »

C-H amination of C12-position

Posted by naturalproductman on January 31, 2013

Shuji Yamashita and co-workers from Tohoku University have reported in Tetrahedron Letters on a C-H amination of the C12-position of steroids.

amination

Tetrahedron Letters paper

Posted in C-H activation, Methodology, Steroids | Leave a Comment »

Spontaneous Diels-Alder

Posted by naturalproductman on January 31, 2013

Craig Merlic and co-workers from UCLA have reported in Organic Letters on a spontaneous transannular Diels-Alder when they used a palladium catalyzed C-C bond forming strategy.

Diels-Alder

OL paper

Posted in Cascade Reactions, Diels-Alder, Methodology, Named Reactions, Palladium, Transition Metal | Leave a Comment »

Huperzine A synthesis

Posted by naturalproductman on January 31, 2013

James White and co-workers have reported in Organic Letters on the synthesis of huperzine A.

huperzine

OL paper

Posted in Alkaloids, Asymmetric, Methodology, Named Reactions, Prins, Total Synthesis | Leave a Comment »

Zamamiphidin A

Posted by naturalproductman on January 31, 2013

Jun’ichi Kobayashi and co-workers from Hokkaido University have reported in Organic Letters on the isolation of zamamiphidin A.

manzamine

OL paper

Posted in Alkaloids | Leave a Comment »

Asperterpenoid A

Posted by naturalproductman on January 31, 2013

Zhigang She and co-workers from Sun-Yat Sen University have reported in Organic Letters on the isolation of asperterpenoid A, which had an IC50 value of 2.2 micromolar against Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB).

ABCDE

OL paper

Posted in Protein Targets, protein tyrosine phosphatase 1B (PTP1B), Terpenoids | Leave a Comment »

Phosphine catalyzed C-N bond formation

Posted by naturalproductman on January 31, 2013

Greg Fu and co-workers reported on a C2-symmetric phosphine catalyst to

phosphine

ACIE paper

Posted in Allenes, C2-Symmetric, Methodology, Organocatalytic | Leave a Comment »

Cinchona alkaloid derived catalyst for epoxidation

Posted by naturalproductman on January 31, 2013

Norio Shibata and co-workers from the Nagoya Institute of Technology have reported in ACIE on an enantioselective epoxidation reaction using a cinchona alkaloid derived catalyst.

cinchona

ACIE paper

Posted in Asymmetric, Epoxidation, Methodology, Organocatalytic | Leave a Comment »

Allylation

Posted by naturalproductman on January 31, 2013

David Lupton and colleague from Monash University have reported in ACIE on a Tsuji-Trost approach for the synthesis of (−)-Kopsihainanine A.

alkaloid

ACIE paper

Posted in Alkaloids, Asymmetric, Methodology, Named Reactions, Palladium, Transition Metal, Tsuji-Trost | Leave a Comment »

Aza-Diels-Alder

Posted by naturalproductman on January 23, 2013

Eric Jacobsen and co-workers have published in JACS on an aza-Diels-Alder. I didn’t know the N. stood for Niels.

 

JACS paper

Posted in Cascade Reactions, Diels-Alder, Methodology, Named Reactions | Leave a Comment »

 
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