Stuart Schreiber and co-workers have reported in Organic Letters on a gold catalyzed coupling of alkynes and propiolic acids to access alpha-pyrones.
Posted by naturalproductman on May 25, 2009
Mark J. Coster in the University of Queensland in Australia has come up with a very nice synthesis of angelmarin (racemic). The activity is 0.01 micrograms/mL towards PANC-1 cells.
Posted by naturalproductman on March 18, 2009
This article in ACIEE explains the Cell paper on how myxopyronin A inhibits an RNA polymerase from a bacteria that causes tuberculosis.