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Archive for the ‘Amides’ Category

Kingianin A synthesis

Posted by naturalproductman on December 29, 2012

Kathlyn Parker and colleague from Stony Brook University have reported in Organic Letters on the synthesis of kingianin A.

kingianin A

OL paper

Posted in Amides, Total Synthesis | Leave a Comment »

Yaku’amides

Posted by naturalproductman on December 1, 2010

Shigeki Matsunaga and co-workers from the University of Tokyo have published in JACS on the isolation of some peptides, yaku’amides A and B, with cytotoxicity against P388 murine leukemia cells with IC50 values of 14 and 4 ng/mL, respectively.

yaku'amides

 

JACS paper

Posted in Amides, Peptides | Leave a Comment »

A Chemical Signal in Yeast

Posted by naturalproductman on September 17, 2010

Robert Cichewicz and co-workers at the University of Oklahoma have published in Organic and Biomolecular Chemistry on the isolation of a metabolite from a Streptomyces species that is responsible in controlling the transition from yeast to mycelia (the long growth form of the fungus).

mutanobactin A


OBC paper

Posted in Amides, Macrocycles | Leave a Comment »

Capsaicin’s Anti-Obesity Effects

Posted by naturalproductman on July 26, 2010

Jong-Won Yu and co-workers at Daegu University have published in the Journal of Proteome Research on the anti-obesity effects of capsaicin, the spicy ingredient in chili peppers.

capsaicin

JPR paper

Posted in Amides, Diseases, Obesity | Leave a Comment »

Kingianin A

Posted by naturalproductman on July 19, 2010

Kingianin A has been isolated from the barks of Endiandra kingiana by Marc Litaudon and co-workers from CNRS.  The biological activity has not been reported but this compound structurally looks interesting.

kingianin

OL paper

Posted in Amides, Polyketides | Leave a Comment »

Papillamide

Posted by naturalproductman on April 8, 2010

Daisuke Uemura and co-workers from Keio University have recently reported in Chemistry Letters on the isolation of a cyclopropane containing compound – papillamide, from the Okinawan red sponge.

papillamide

Chemistry Letters paper

Posted in Amides, Fatty Acids | Leave a Comment »

8-Epi-Malyngamide C

Posted by naturalproductman on February 18, 2010

The epimer of malyngamide at the C8 position was isolated by Hendrik Luesch and co-workers at the University of Florida.  The biological activity did not seem to change significantly between the two epimers.

malyngamide C

JNP paper

Posted in Amides | Leave a Comment »

 
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