Kingianin A synthesis

Kathlyn Parker and colleague from Stony Brook University have reported in Organic Letters on the synthesis of kingianin A.

OL paper

Yaku’amides

Shigeki Matsunaga and co-workers from the University of Tokyo have published in JACS on the isolation of some peptides, yaku’amides A and B, with cytotoxicity against P388 murine leukemia cells with IC50 values of 14 and 4 ng/mL, respectively.

 

JACS paper

A Chemical Signal in Yeast

Robert Cichewicz and co-workers at the University of Oklahoma have published in Organic and Biomolecular Chemistry on the isolation of a metabolite from a Streptomyces species that is responsible in controlling the transition from yeast to mycelia (the long growth form of the fungus).

OBC paper

Capsaicin’s Anti-Obesity Effects

Jong-Won Yu and co-workers at Daegu University have published in the Journal of Proteome Research on the anti-obesity effects of capsaicin, the spicy ingredient in chili peppers.

JPR paper

Kingianin A

Kingianin A has been isolated from the barks of Endiandra kingiana by Marc Litaudon and co-workers from CNRS.  The biological activity has not been reported but this compound structurally looks interesting.

OL paper

Papillamide

Daisuke Uemura and co-workers from Keio University have recently reported in Chemistry Letters on the isolation of a cyclopropane containing compound – papillamide, from the Okinawan red sponge.

Chemistry Letters paper

8-Epi-Malyngamide C

The epimer of malyngamide at the C8 position was isolated by Hendrik Luesch and co-workers at the University of Florida.  The biological activity did not seem to change significantly between the two epimers.

JNP paper