Naturalproductman’s Blog

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Archive for the ‘Antibiotics’ Category

Baulamycins

Posted by naturalproductman on January 17, 2014

David Sherman and co-workers found some new natural products with anti-biotic activities (IC50s ranging from low to high micromolar range) and reported this in JACS.
baulamycins

 

JACS paper

Posted in Antibiotics, Polyketides | Leave a Comment »

BE-43472B synthesis

Posted by naturalproductman on May 17, 2013

Keisuke Suzuki and co-workers at Tokyo Institute of Technology have reported in ACIE on the synthesis of

antibiotic

ACIE paper

Posted in Antibiotics, Methodology, Total Synthesis | Leave a Comment »

Pactamycin synthesis

Posted by naturalproductman on April 12, 2013

Jeffrey Johnson and co-workers at UNC have reported in Science on the synthesis of pactamycin.

 

Science paper

Posted in Antibiotics, Total Synthesis | Leave a Comment »

Tetarimycin A

Posted by naturalproductman on November 27, 2012

Sean Brady and co-workers from Rockefeller University have reported in JACS on the isolation of tetarimycin A, which had a MIC (minimum inhibitory concentration) of 1.5 micrograms/mL against S. aureus 6538P.

antibiotic

JACS paper

Posted in Antibiotics, Chemical Biology, Polyketides | Leave a Comment »

Obtusinone A

Posted by naturalproductman on December 11, 2011

Chatchanok Karalai and co-workers at Prince of Songkla University have reported in Tetrahedron on an diterpene with anti-inflammatory properties.

obtusinone

Tetrahedron paper

Posted in Anti-inflammatory, Antibiotics, Diterpene | Leave a Comment »

Fulvynes

Posted by naturalproductman on December 9, 2011

Maria Letizia Ciavatta and co-workers at Istituto di Chimica Biomolecolare in Italy have reported in Tetrahedron on the isolation of fulvyne.

fulvyne

Tetrahedron paper

Posted in Antibiotics, Polyynes | Leave a Comment »

Erogorgiaene synthesis

Posted by naturalproductman on October 2, 2011

Varinder Aggarwal and co-workers at the University of Bristol have reported in JACS on a synthesis of erogorgiaene.

erogorgiaene

JACS paper

Posted in Antibiotics, Aromatic, Diterpene, Methodology, Total Synthesis | Leave a Comment »

Pestalotheols

Posted by naturalproductman on September 18, 2011

Karsten Krohn and co-workers at the University of Paderborn have reported in European JOC on the isolation of some biologically active tetrahydrofurans.

pestalotheols

European JOC paper

Posted in Antibiotics, Tetrahydrofuran | Leave a Comment »

Homoserine transacetylase inhibitors

Posted by naturalproductman on August 11, 2011

Gerard Wright and co-workers from McMaster University have reported in the Journal of Antibiotics on the inhibitory activity of beta-lactone compounds against homoserine transacetylase.

 

Journal of Antibiotics paper

Posted in Antibiotics, Lactones | Leave a Comment »

Streptolydigin activities

Posted by naturalproductman on July 25, 2011

Sergey Kozmin and co-workers from the University of Chicago have reported in JACS on their streptolydigin syntheses and antibacterial activity.

antibacterial

JACS paper

Posted in Antibiotics, Methodology, Polyenes | Leave a Comment »

 
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