Naturalproductman’s Blog

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Archive for the ‘Aromatic’ Category

Lomaiviticins and DNA damage

Posted by naturalproductman on July 16, 2014

Seth Herzon and co-workers have reported in ACIE on the DNA damage activity of lomaiviticins.

lomaiviticins

ACIE paper

Posted in Aromatic, Chemical Biology | Leave a Comment »

Kuwanons I and J and Brosimones A and B syntheses

Posted by naturalproductman on July 12, 2014

Xiaoguang Lei and co-workers at Peking University have reported in ACIE on the synthesis of kuwanons I and J.
aromatic

ACIE paper

Posted in Antioxidants, Aromatic, Total Synthesis | Leave a Comment »

Vaticanol A synthesis

Posted by naturalproductman on May 22, 2014

Scott Snyder and co-workers from Scripps (Florida) have reported in ACIE on the synthesis of vaticanol A.

vaticanol

ACIE paper

Posted in Aromatic, Methodology, Total Synthesis | Leave a Comment »

Linoxepin synthesis

Posted by naturalproductman on April 18, 2013

Mark Lautens and co-workers at the University of Toronto have reported in ACIE on the synthesis of linoxepin.

linoxepin

ACIE paper

Posted in Aromatic, Polyketides, Total Synthesis | Leave a Comment »

Calvicularin synthesis

Posted by naturalproductman on January 10, 2013

Christopher Beaudry and co-workers from Oregon State have reported in Organic Letters on a synthesis of cavicularin using a vinyl sulfone for a Diels-Alder substrate.

calvicularin

OL paper

Posted in Aromatic, Cascade Reactions, Diels-Alder, Methodology, Named Reactions, Polyketides | Leave a Comment »

HIV-1 reverse transcriptase structure with catechol diether

Posted by naturalproductman on November 19, 2012

Karen Anderson and co-workers at Yale have reported in JACS on a crystal structures of HIV-1 reverse transcriptase with catechol diether drugs.

HIV

JACS paper

Posted in Aromatic, Diseases, Enzymes, HIV, Proteins | Leave a Comment »

Xestoquinones

Posted by naturalproductman on September 7, 2012

Daniel Nagle and co-workers from the University of Mississippi have reported in JNP on the isolation of xestoquinones.

xestoquinones

JNP paper

Posted in Aromatic, breast, Cancer | Leave a Comment »

No that’s not BINAP

Posted by naturalproductman on April 25, 2012

N. P. Dhammika Nanayakkara and co-workers from the University of Mississippi have reported in JNP on the isolation of some compounds that look like BINAP.

antiprotozoal

JNP paper

Posted in Aromatic, C2-Symmetric | Leave a Comment »

Angelone synthesis

Posted by naturalproductman on April 25, 2012

Zhigang Weng and co-workers from Shenzhen University have reported in Tetrahedron on a synthesis of angelone.  The highlight is the cascade reaction forming the final product.

angelone

Tetrahedron paper

Posted in Aromatic, Cascade Reactions, Mechanistic, Methodology, One pot, Total Synthesis | Leave a Comment »

Psoromic acid inhibits RabGGTase

Posted by naturalproductman on April 23, 2012

Yao-Wen Wu and co-workers at Max Planck have reported in JACS on the inhibition of RabGGTase using psoromic acid.

psoromic acid

JACS paper

Posted in Aromatic, Cancer, Carboxylic acids, Post-Translational Modification, Protein Targets | Leave a Comment »

 
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