Naturalproductman’s Blog

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Archive for the ‘Axial Chirality’ Category

Access to axially chiral compounds

Posted by naturalproductman on May 2, 2014

Scott Miller and co-workers published in Nature on the bromination of a benzamide using a peptide derived catalyst.

 

Nature paper

Posted in Asymmetric, Axial Chirality, Methodology | Leave a Comment »

Atropisomers with peptoids

Posted by naturalproductman on June 25, 2011

Kent Kirshenbaum and co-workers at NYU have reported in JACS on peptide like atropisomers.   If you’re not familiar with atropisomers just think of the BINAP ligands that Noyori used for asymmetric hydrogenations.

atropisomers

JACS paper

Posted in Atropisomers, Axial Chirality, Methodology | Leave a Comment »

Synthesis of Rhazinilam

Posted by naturalproductman on August 27, 2010

Armen Zakarian and co-worker have published in UCSB on a Heck cyclization approach to access rhazinilam.

Heck

OL paper

Posted in Alkaloids, Asymmetric, Axial Chirality, cross coupling, Heck, Methodology, Palladium, Transition Metal | Leave a Comment »

 
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