Naturalproductman’s Blog

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Archive for the ‘C2-Symmetric’ Category

Disorazole through cross metathesis

Posted by naturalproductman on November 8, 2014

Hoveyda and co-workers from Boston College have reported in JACS on a Z-selective cross coupling to access this C2-symmetric molecule – using alkenyl boronate and alkenyl iodide moieties.
metathesis

JACS paper

Posted in Alkaloids, C2-Symmetric, Metathesis, Methodology, Oxazoles, Ruthenium, Transition Metal | Leave a Comment »

Bislactone desymmetrization

Posted by naturalproductman on July 27, 2014

Jieping Zhu and co-workers have reported in ACIE on the synthesis of rhazinilam and leucomidine B.

desymmetrize

ACIE paper

Posted in Alkaloids, Asymmetric, C2-Symmetric, Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

Marinomycin A synthesis

Posted by naturalproductman on June 28, 2014

Susumi Hatakeyama and co-workers from Nagasaki University have reported in ACIE on the synthesis of marinomycin A.

marinomycin A

ACIE paper

Posted in C2-Symmetric, Methodology, Polyketides, Total Synthesis | Leave a Comment »

Logeracemin A

Posted by naturalproductman on May 21, 2014

Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in JACS on the isolation of logeracemin A.

logeracemin A

JACS paper

Posted in Alkaloids, C2-Symmetric, Diseases, HIV | Leave a Comment »

Amphidinolides C and F syntheses

Posted by naturalproductman on July 11, 2013

Rich Carter and colleague have reported in JACS on a synthesis of amphidinolides C and F.

amphidinolide

JACS paper

Posted in C2-Symmetric, Macrolides, Methodology, Total Synthesis | Leave a Comment »

Kinetic resolution with phosphoric acid

Posted by naturalproductman on March 13, 2013

William Roush and co-workers have reported in Org Lett on a kinetic resolution using phosphoric acid.

kinetic resolution

OL paper

Posted in C2-Symmetric, Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

Phosphine catalyzed C-N bond formation

Posted by naturalproductman on January 31, 2013

Greg Fu and co-workers reported on a C2-symmetric phosphine catalyst to

phosphine

ACIE paper

Posted in Allenes, C2-Symmetric, Methodology, Organocatalytic | Leave a Comment »

No that’s not BINAP

Posted by naturalproductman on April 25, 2012

N. P. Dhammika Nanayakkara and co-workers from the University of Mississippi have reported in JNP on the isolation of some compounds that look like BINAP.

antiprotozoal

JNP paper

Posted in Aromatic, C2-Symmetric | Leave a Comment »

Rhizopodin synthesis

Posted by naturalproductman on April 24, 2012

Dirk Menche and co-workers from Universität Heidelberg have reported in ACIE on the synthesis of rhizopodin.

rhizopodin

ACIE paper

Posted in C2-Symmetric, Macrolides, Methodology, Oxazoles, Total Synthesis | Leave a Comment »

Mycocyclosin synthesis

Posted by naturalproductman on April 21, 2012

Craig Hutton and co-workers from the University of Melbourne have reported in Organic Letters on the synthesis of mycocyclosin.

mycocyclosin

OL paper

Posted in Alkaloids, C2-Symmetric, Methodology, Total Synthesis | Leave a Comment »

 
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