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Archive for the ‘Depsipeptides’ Category

Stellatolides

Posted by naturalproductman on May 6, 2014

Carmen Cuevas and co-workers from PharmaMar in Spain have reported in JACS on the isolation and syntheses of stellatolides.

stellatolides

JACS paper

Posted in Cancer, Depsipeptides, Peptides, Total Synthesis | Leave a Comment »

Aetheramides A and B

Posted by naturalproductman on May 29, 2012

Rolf Mueller and co-workers at Universität des Saarlandes have reported in Organic Letters on some anti-HIV depsipeptides with 15 nM IC50 values.

depsipeptides

OL paper

Posted in Depsipeptides, Diseases, HIV | Leave a Comment »

Compounds from a fungus

Posted by naturalproductman on October 8, 2011

Nicholas Oberlies and co-workers at UNC Greensboro have reported in the Journal of Natural Products on the isolation of some peptides and sesquiterpenoids from the terrestrial filamentous fungus, Trichothecium sp.

fungus

JNP paper

Posted in Depsipeptides, Polyenes, Sesquiterpenoids | Leave a Comment »

Koshikamides

Posted by naturalproductman on April 20, 2010

Carole Bewley and co-workers at the NIH have isolated some peptides tested with the HIV-1 infectivity assay against a CCR5-using viral envelope in order to test their inhibition of HIV-1 entry.  Koshikamides F and H had inhibited HIV entry with IC50 values of 2.3 and 5.5 micromolar.

HIV inhibitor

JOC paper

Posted in Depsipeptides, Peptides | Leave a Comment »

 
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