Naturalproductman’s Blog

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Archive for the ‘Diseases’ Category

ZMapp vs. ebola

Posted by naturalproductman on August 30, 2014

Gary Kopinger and co-workers from the University of Manitoba have reported in Nature on ZMapp’s reversion of the ebola virus.
Nature paper

Posted in Anti-viral, Diseases | Leave a Comment »

Aspergillomarasmine A

Posted by naturalproductman on June 28, 2014

Gerald Wright and co-workers from McMaster University in Canada have reported in Nature on aspergillomarasmine A being a good inhibitor for the New Dehli Metallo beta-lactamase 1 (NDM-1) enzyme.

 

Nature paper

Posted in Amino Acids, Antibiotics, Diseases | 1 Comment »

Anti-malarial pyrrolopyrazines

Posted by naturalproductman on June 7, 2014

Gisbert Schneider and co-workers from ETH Zurich have reported in ACIE on some anti-malarial pyrrolopyrazines.

ACIE paper

Posted in Diseases, Malaria, Unnatural Products | Leave a Comment »

Zoaramine

Posted by naturalproductman on June 3, 2014

Antonio Hernandez Daranas and co-workers at University La Laguna in Spain have reported in Organic Letters on the isolation of zoaramine.
zoaramine

OL paper

Posted in Alkaloids, Osteoporosis | Leave a Comment »

Logeracemin A

Posted by naturalproductman on May 21, 2014

Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in JACS on the isolation of logeracemin A.

logeracemin A

JACS paper

Posted in Alkaloids, C2-Symmetric, Diseases, HIV | Leave a Comment »

Cardamom peroxide synthesis

Posted by naturalproductman on March 27, 2014

Thomas Maimone and co-worker from UC Berkeley have reported in JACS on a 4-step synthesis of cardamom peroxide from myrtenal.

 

 

JACS paper

Posted in Diseases, Malaria, Peroxides, Total Synthesis | Leave a Comment »

Sweriledugenin A

Posted by naturalproductman on December 30, 2013

Ji-Jun Chen and co-workers at the Kunming Institute of Botany have reported in Org Lett on the isolation of sweriledugenin A.

lactone

OL paper

Posted in Anti-viral, Diseases, Lactones, Mass Spectrometry | Leave a Comment »

MA026 synthesis

Posted by naturalproductman on December 9, 2013

Fumio Sugawara and co-workers at the Tokyo University of Science have reported in JACS on the synthesis of MA026 and its anti-hepatitis C virus activity.

HCV

JACS paper

Posted in Anti-viral, Diseases, Hepatitis C, Peptides, Total Synthesis | Leave a Comment »

Samroiyotmycins A and B

Posted by naturalproductman on August 3, 2013

Pattama Pittayakhajonwut and co-workers from BIOTEC in Thailand have reported in Tetrahedron on the isolation of samroiyotmycins A and B, anti-malarial macrolides from bacteria.

ssamroiyotmycin

Tetrahedron paper

Posted in Diseases, Macrolides, Malaria | Leave a Comment »

Mbandakamines A and B

Posted by naturalproductman on May 16, 2013

Gerhard Bringmann and co-workers at the University of Wurzberg have reported in OL on the isolation of anti-malarial mbandakamines A and B.
mbandakamines

OL paper

Posted in Alkaloids, Diseases, Malaria | Leave a Comment »

 
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