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Archive for the ‘Diseases’ Category

Myrioneurinol synthesis

Posted by naturalproductman on November 4, 2014

Steven Weinreb and colleague at Penn State have reported in ACIE on the synthesis of myrioneurinol.

alkaloid

ACIE paper

Posted in Total Synthesis, Diseases, Malaria | Leave a Comment »

ZMapp vs. ebola

Posted by naturalproductman on August 30, 2014

Gary Kopinger and co-workers from the University of Manitoba have reported in Nature on ZMapp’s reversion of the ebola virus.
Nature paper

Posted in Anti-viral, Diseases | Leave a Comment »

Aspergillomarasmine A

Posted by naturalproductman on June 28, 2014

Gerald Wright and co-workers from McMaster University in Canada have reported in Nature on aspergillomarasmine A being a good inhibitor for the New Dehli Metallo beta-lactamase 1 (NDM-1) enzyme.

 

Nature paper

Posted in Amino Acids, Antibiotics, Diseases | 1 Comment »

Anti-malarial pyrrolopyrazines

Posted by naturalproductman on June 7, 2014

Gisbert Schneider and co-workers from ETH Zurich have reported in ACIE on some anti-malarial pyrrolopyrazines.

ACIE paper

Posted in Diseases, Malaria, Unnatural Products | Leave a Comment »

Zoaramine

Posted by naturalproductman on June 3, 2014

Antonio Hernandez Daranas and co-workers at University La Laguna in Spain have reported in Organic Letters on the isolation of zoaramine.
zoaramine

OL paper

Posted in Alkaloids, Osteoporosis | Leave a Comment »

Logeracemin A

Posted by naturalproductman on May 21, 2014

Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in JACS on the isolation of logeracemin A.

logeracemin A

JACS paper

Posted in Alkaloids, C2-Symmetric, Diseases, HIV | Leave a Comment »

Cardamom peroxide synthesis

Posted by naturalproductman on March 27, 2014

Thomas Maimone and co-worker from UC Berkeley have reported in JACS on a 4-step synthesis of cardamom peroxide from myrtenal.

 

 

JACS paper

Posted in Diseases, Malaria, Peroxides, Total Synthesis | Leave a Comment »

Sweriledugenin A

Posted by naturalproductman on December 30, 2013

Ji-Jun Chen and co-workers at the Kunming Institute of Botany have reported in Org Lett on the isolation of sweriledugenin A.

lactone

OL paper

Posted in Anti-viral, Diseases, Lactones, Mass Spectrometry | Leave a Comment »

MA026 synthesis

Posted by naturalproductman on December 9, 2013

Fumio Sugawara and co-workers at the Tokyo University of Science have reported in JACS on the synthesis of MA026 and its anti-hepatitis C virus activity.

HCV

JACS paper

Posted in Anti-viral, Diseases, Hepatitis C, Peptides, Total Synthesis | Leave a Comment »

Samroiyotmycins A and B

Posted by naturalproductman on August 3, 2013

Pattama Pittayakhajonwut and co-workers from BIOTEC in Thailand have reported in Tetrahedron on the isolation of samroiyotmycins A and B, anti-malarial macrolides from bacteria.

ssamroiyotmycin

Tetrahedron paper

Posted in Diseases, Macrolides, Malaria | Leave a Comment »

 
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