Mbandakamines A and B

Gerhard Bringmann and co-workers at the University of Wurzberg have reported in OL on the isolation of anti-malarial mbandakamines A and B.

OL paper

Amphilectene synthesis

Ryan Shenvi and colleague at Scripps have reported in JACS on the synthesis of amphilectene, an antimalarial compound.

JACS paper

Gracilioether H has anti-malarial activity

Angela Zampella and co-workers have reported in Tetrahedron on the isolation of gracilioethers.  Gracilioether H had anti-malarial activity.

Tetrahedron paper

Epicoccin G, 8,8ʹ-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E and Haematocin – total synthesis

Nicolaou and co-workers have reported in JACS on the syntheses and anti-malarial activities of some polythio compounds.

JACS paper

Artemisinin synthesis

Silas Cook and colleague at Indiana University have reported in JACS on a synthesis of artemisinin using a molybdenum promoted in situ formation of singlet oxygen to form the endoperoxide.

JACS paper

Flinderole A synthesis

Jeremy May and colleague at the University of Houston have reported in JACS on a synthesis of flinderole A.

JACS paper

Artemisinin resistance is from the parasite’s genes

Timothy Anderson and co-workers from the Texas Biomedical Research Institute in San Antonio have reported in Science on the basis of artemisinin resistance in some plasmodium falciporum strains.

Science paper

Diarylheptanoid glucosides

Marc Litaudon and co-workers from CNRS have reported in European JOC on the isolation of diarylheptanoid glucosides.

European JOC paper

Artemisinin chemistry

Giancarlo Marconi and co-workers have reported in Tetrahedron Letters on a reduction of artemisinin, an antimalarial compound, to break down the peroxide bond and open the ring.

TL paper

Indole alkaloids

Lengo Mambu and co-workers have reported in Phytochemistry on some indole alkaloids with mild anti-malarial activities.

Phytochemistry paper