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Archive for the ‘Malaria’ Category

Anti-malarial pyrrolopyrazines

Posted by naturalproductman on June 7, 2014

Gisbert Schneider and co-workers from ETH Zurich have reported in ACIE on some anti-malarial pyrrolopyrazines.

ACIE paper

Posted in Diseases, Malaria, Unnatural Products | Leave a Comment »

Cardamom peroxide synthesis

Posted by naturalproductman on March 27, 2014

Thomas Maimone and co-worker from UC Berkeley have reported in JACS on a 4-step synthesis of cardamom peroxide from myrtenal.

 

 

JACS paper

Posted in Diseases, Malaria, Peroxides, Total Synthesis | Leave a Comment »

Samroiyotmycins A and B

Posted by naturalproductman on August 3, 2013

Pattama Pittayakhajonwut and co-workers from BIOTEC in Thailand have reported in Tetrahedron on the isolation of samroiyotmycins A and B, anti-malarial macrolides from bacteria.

ssamroiyotmycin

Tetrahedron paper

Posted in Diseases, Macrolides, Malaria | Leave a Comment »

Mbandakamines A and B

Posted by naturalproductman on May 16, 2013

Gerhard Bringmann and co-workers at the University of Wurzberg have reported in OL on the isolation of anti-malarial mbandakamines A and B.
mbandakamines

OL paper

Posted in Alkaloids, Diseases, Malaria | Leave a Comment »

Amphilectene synthesis

Posted by naturalproductman on November 16, 2012

Ryan Shenvi and colleague at Scripps have reported in JACS on the synthesis of amphilectene, an antimalarial compound.

amphilectene

JACS paper

Posted in Diseases, Malaria, Terpenoids, Total Synthesis | Leave a Comment »

Gracilioether H has anti-malarial activity

Posted by naturalproductman on October 23, 2012

Angela Zampella and co-workers have reported in Tetrahedron on the isolation of gracilioethers.  Gracilioether H had anti-malarial activity.

gracilioether H

Tetrahedron paper

Posted in Diseases, Malaria, Methodology, Peroxides | Leave a Comment »

Epicoccin G, 8,8ʹ-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E and Haematocin – total synthesis

Posted by naturalproductman on September 18, 2012

Nicolaou and co-workers have reported in JACS on the syntheses and anti-malarial activities of some polythio compounds.

JACS paper

Posted in Alkaloids, Diseases, Malaria, Methodology, Total Synthesis | Leave a Comment »

Artemisinin synthesis

Posted by naturalproductman on August 6, 2012

Silas Cook and colleague at Indiana University have reported in JACS on a synthesis of artemisinin using a molybdenum promoted in situ formation of singlet oxygen to form the endoperoxide.

hydrogen peroxide

JACS paper

Posted in Cascade Reactions, Diseases, Malaria, Methodology, Molybdenum, Total Synthesis, Transition Metal | Leave a Comment »

Flinderole A synthesis

Posted by naturalproductman on April 11, 2012

Jeremy May and colleague at the University of Houston have reported in JACS on a synthesis of flinderole A.

flinderole

JACS paper

Posted in Alkaloids, Diseases, Indoles, Malaria, Methodology, Total Synthesis | Leave a Comment »

Artemisinin resistance is from the parasite’s genes

Posted by naturalproductman on April 5, 2012

Timothy Anderson and co-workers from the Texas Biomedical Research Institute in San Antonio have reported in Science on the basis of artemisinin resistance in some plasmodium falciporum strains.

Science paper

Posted in Diseases, Malaria | Leave a Comment »

 
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