Methyl sarcotroates

Yue-Wei Guo and co-workers at the Chinese Academy of Sciences have reported in Organic Letters on the isolation of some diterpenoids.

OL paper

Maeocrystal V synthesis

Danishefsky and colleague have reported in JACS on a racemic synthesis of maeocrystal V.

JACS paper

Oxyingenol synthesis

Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of oxyingenol.

ACIE paper

Tinocrispol A

Shoei-Sheng Lee and co-workers from National Taiwan University have reported in JNP on the isolation of some hypoglycemic compounds.

JNP paper

Bigunningines

Yang Ye and co-workers at the Shanghai Institute of Materia Medica have reported in Organic Letters on the isolation of bicunningines, dimeric diterpenoids.

OL paper

Neolaxiflorin A

Han-Dong Sun and co-workers at the Kunming Institute of Botany have reported in Organic Letters on the isolation of neolaxiflorin A.

OL paper

Trigocherrin A

Marc Litaudon and co-workers at CNRS have reported in Organic Letters on a chlorinated diterpenoid orthoester.

OL paper

Chamobtusin synthesis

Sakae Aoyagi and colleague at the Tokyo Pharmaceutical University have reported in Chem Comm on the synthesis of chamobtusin, a diterpenoid alkaloid.  A tungsten mediated oxidation protocol was used to access the pyrrole from a tetrahydropyrrole.

Chem Comm paper

Salvileucalin C

Koichi Takeya and co-workers from Tokyo University of Pharmacy and Life Sciences have reported in Tetrahedron Letters on the structure of salvileucalin C isolated from a plant called Salvia leucantha.

 

TL paper

Spirocurcasone

Orazio Taglialatela-Scafati and co-workers at Universita di Napoli have published in Organic Letters on the isolation of some diterpenoids including a novel spirocycle, spirocurcasone, however, this new spirocyclic compound did not seem to have any biological activity.  A related structure, curcasone C, had an IC50 value of 0.08 micrograms/mL against the L5178Y (mouse lymphoma) cell line.

 

OL paper