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Archive for the ‘Diterpenoids’ Category

VUlgarisin A

Posted by naturalproductman on May 6, 2014

Weidong Pan and co-workers from the Chinese Academy of Sciences have reported in Organic Letters on the isolation of vulgarisin A.

vulgarisin A

OL paper

Posted in Cancer, Cyclobutanes, Diterpenoids, lung | Leave a Comment »

Ingenol from carene

Posted by naturalproductman on August 23, 2013

Baran and co-workers published in Science on the synthesis of ingenol.

 

Science paper

Posted in Diterpenoids | Leave a Comment »

Methyl sarcotroates

Posted by naturalproductman on December 29, 2012

Yue-Wei Guo and co-workers at the Chinese Academy of Sciences have reported in Organic Letters on the isolation of some diterpenoids.

PTPB1

OL paper

Posted in Diterpenoids, Protein Targets, protein tyrosine phosphatase 1B (PTP1B) | Leave a Comment »

Maeocrystal V synthesis

Posted by naturalproductman on November 6, 2012

Danishefsky and colleague have reported in JACS on a racemic synthesis of maeocrystal V.

maeocrystal V

JACS paper

Posted in Cascade Reactions, Cycloaddition, Diels-Alder, Diterpenoids, Methodology, Named Reactions, Pericyclic reactions, Total Synthesis | Leave a Comment »

Oxyingenol synthesis

Posted by naturalproductman on April 17, 2012

Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of oxyingenol.

oxyingenol

ACIE paper

Posted in Diseases, Diterpenoids, HIV, Metathesis, Methodology, Ruthenium, Sigmatropic Rearrangements, Total Synthesis, Transition Metal | Leave a Comment »

Tinocrispol A

Posted by naturalproductman on February 10, 2012

Shoei-Sheng Lee and co-workers from National Taiwan University have reported in JNP on the isolation of some hypoglycemic compounds.

glucose lowering

JNP paper

Posted in Diabetes Type 1, Diseases, Diterpenoids | Leave a Comment »

Bigunningines

Posted by naturalproductman on December 30, 2011

Yang Ye and co-workers at the Shanghai Institute of Materia Medica have reported in Organic Letters on the isolation of bicunningines, dimeric diterpenoids.

dimer

OL paper

Posted in Dimer, Diterpenoids | Leave a Comment »

Neolaxiflorin A

Posted by naturalproductman on December 19, 2011

Han-Dong Sun and co-workers at the Kunming Institute of Botany have reported in Organic Letters on the isolation of neolaxiflorin A.

neolaxiflorin A

OL paper

Posted in Diterpenoids | Leave a Comment »

Trigocherrin A

Posted by naturalproductman on December 19, 2011

Marc Litaudon and co-workers at CNRS have reported in Organic Letters on a chlorinated diterpenoid orthoester.

trigocherrin

OL paper

Posted in Diterpenoids | Leave a Comment »

Chamobtusin synthesis

Posted by naturalproductman on June 5, 2011

Sakae Aoyagi and colleague at the Tokyo Pharmaceutical University have reported in Chem Comm on the synthesis of chamobtusin, a diterpenoid alkaloid.  A tungsten mediated oxidation protocol was used to access the pyrrole from a tetrahydropyrrole.

tungsten

Chem Comm paper

Posted in Alkaloids, Cascade Reactions, Diterpenoids, Methodology, Michael, Named Reactions, Ring forming, Transition Metal, Tungsten | Leave a Comment »

 
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