Naturalproductman’s Blog

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Archive for the ‘Flavonoids’ Category

polyflavanostilbene A

Posted by naturalproductman on January 17, 2013

Peicheng Zhang and co-workers from Chinese Academy of Medical Sciences have reported in Org Lett on the isolation of polyflavanostilbene A.

polyflavanostilbene A

OL paper

Posted in Flavonoids, Glycosides | Leave a Comment »

Anti-HSV flavonoids

Posted by naturalproductman on March 30, 2012

Xin-Sheng Yao and co-workers from Jinan University have reported on the isolation of some flavonoids  called houttuynoids A-E with anti-Herpes Simplex virus activity (IC50 ~ 45 micromolar).

HSV

OL paper

Posted in Diseases, Flavonoids, Herpes Simplex virus | Leave a Comment »

Longeracemosones

Posted by naturalproductman on July 3, 2011

Somsak Ruchirawat and co-workers from Chulabhorn Research Institute in Thailand have reported in the European JOC on the isolation of longeracemosones A–F, which were found to have inhibitory activity against aromatase.

aromatase

European JOC paper

Posted in Flavonoids | 1 Comment »

Longeracemosones A-F

Posted by naturalproductman on June 5, 2011

Somsak Ruchirawat and co-workers at Chulabhorn Graduate Institute and the Center for Environmental Health in Thailand have reported in the European Journal of Organic Chemistry on the isolation of longeracemosones, which had anti-aromatase activity.

aromatase

European JOC paper

Posted in Flavonoids | Leave a Comment »

Austocystin D and MDR1

Posted by naturalproductman on February 28, 2011

Henry Pelish and co-workers at Makoto Life Sciences have reported in the Journal Natural Products on the compound, austocystin D, which gets activated by a cytochrome P450 enzyme (CYP3A4) and then does the damage to the cells.

austocystin

 

JNP paper

Posted in Chemical Biology, Flavonoids, Polyketides | Leave a Comment »

Flavonoid and Alzheimer’s Tau Protein

Posted by naturalproductman on September 7, 2010

Tian-Ming Yao and co-workers at Tongji University have published in the Bulletin of Chemical Society of Japan on the isolation of a flavonoid that inhibited aggregation of the tau protein into paired helical fragments (PHFs).

flavonoids

BCSJ paper

Posted in Alzheimer's, Chemical Biology, Diseases, Flavonoids | Leave a Comment »

Cytotoxic Flavonoids

Posted by naturalproductman on March 22, 2010

Shigetoshi Kadota and co-workers at the University of Toyama have recently reported in the Journal of Natural Products on the isolation of the flavonoid, (7′′R)-8-[1-(4′-hydroxy-3′-methoxyphenyl)prop-2-en-1-yl]galangin, from the plant, Mexican propolis.  This aromatic compound was found to have an PC50 value of against PANC-1 human pancreatic cells.

flavonoid


JNP paper

Posted in Aromatic, Flavonoids | Leave a Comment »

 
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