Naturalproductman’s Blog

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Archive for the ‘Indolizidines’ Category

Towards allopumiliotoxin

Posted by naturalproductman on January 25, 2012

Srivari Chandrasekhar and co-workers at Indian Institute of
Chemical Technology have reported in Chemistry – a European Journal on their progress towards allopumiliotoxins.

indolizidine

Chemistry – a European Journal paper

Posted in Cascade Reactions, Indolizidines, Metal-halogen exchange, Methodology | Leave a Comment »

Dienamine cyclization

Posted by naturalproductman on January 24, 2012

Ryan Shenvi and co-workers from Scripps have reported in JACS on a cyclization of a dienamine.

amino

JACS paper

Posted in Cascade Reactions, Indolizidines, Methodology | 1 Comment »

Michael followed by Pictet-Spengler

Posted by naturalproductman on August 29, 2011

Xiaoyu Wu and co-workers at Shanghai University have reported in Chemistry a European Journal on a reaction that involves two named reaction using an indole tethered with a primary amine and an alkynoate as the subtrates.

Michael

Chemistry a European Journal paper

Posted in Cascade Reactions, Indoles, Indolizidines, Methodology, Michael, Named Reactions, Organocatalytic, Pictet-Spengler | Leave a Comment »

Flueggines A and B

Posted by naturalproductman on July 5, 2011

Wen-Cai Ye and co-workers at Jinan University have reported in Organic Letters on the isolation of flueggines A and B.  Flueggine B had activity with an IC50 values of 135 ± 5 and 147 ± 3 nM against MCF-7 and MDA-MB-231 cells, respectively.

flueggines

OL paper

Posted in Alkaloids, breast, Cancer, Indoles, Indolizidines, Isoxazolidines | Leave a Comment »

 
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