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Archive for the ‘Iridoids’ Category

9-deoxygelsemide

Posted by naturalproductman on December 29, 2009

Giovanni Vidari and co-workers at the Universitat di Pavia in Italy have recently published in Organic Letters on the synthesis of 9-deoxygelsemide, a compound foud from a plant Gelsemium elegans Benth. found in Japan. This compound had an EC50 of 22.6 micromolar against A549 lung tumor cells.

deoxygelsemide

OL paper

Posted in Cascade Reactions, Iridoids, Mechanistic, Methodology, Ring forming | Leave a Comment »

Hepatitis C Virus Entry Inhibitors

Posted by naturalproductman on November 12, 2009

Lamiridosins A and B, dihydropyranyl containing bicyclic compounds from the flowers of Lamium album were found to inhibit cell entry for the hepatitis C virus at an IC50 of 2.31 micromolar.  Hongjie Zhang and co-workers at UIC have recently published their findings in the Journal of Natural Products.

lamiridosins

JNP paper

Posted in Iridoids | Leave a Comment »

 
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