9-deoxygelsemide

Giovanni Vidari and co-workers at the Universitat di Pavia in Italy have recently published in Organic Letters on the synthesis of 9-deoxygelsemide, a compound foud from a plant Gelsemium elegans Benth. found in Japan. This compound had an EC50 of 22.6 micromolar against A549 lung tumor cells.

OL paper

Hepatitis C Virus Entry Inhibitors

Lamiridosins A and B, dihydropyranyl containing bicyclic compounds from the flowers of Lamium album were found to inhibit cell entry for the hepatitis C virus at an IC50 of 2.31 micromolar.  Hongjie Zhang and co-workers at UIC have recently published their findings in the Journal of Natural Products.

JNP paper