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Archive for the ‘Lactones’ Category

Sweriledugenin A

Posted by naturalproductman on December 30, 2013

Ji-Jun Chen and co-workers at the Kunming Institute of Botany have reported in Org Lett on the isolation of sweriledugenin A.

lactone

OL paper

Posted in Anti-viral, Diseases, Lactones, Mass Spectrometry | Leave a Comment »

Ophiodilactones A and B syntheses

Posted by naturalproductman on December 13, 2013

Susumi Hatakeyama and co-workers from Nagasaki University have reported in ACIE on the syntheses of ophiodilactones A and B.

lactone
ACIE paper

Posted in Lactones, Total Synthesis | Leave a Comment »

Towards Bielschowskysin

Posted by naturalproductman on June 7, 2013

Johann Mulzer and co-workers have published in Organic Letters on their progress towards

bielschowskysin
OL paper

Posted in Lactones, Methodology | Leave a Comment »

Structural reassignment of aquatolide using DFT/NMR

Posted by naturalproductman on November 6, 2012

Dean Tantillo and co-workers have used Gaussian in conjunction with NMR and crystallography to reassign the structure of aquatolide.

structural reassignment

JACS paper

Posted in Computational, DFT, Lactones, Sesquiterpenes | Leave a Comment »

Anti-HIV schilancitrilactone

Posted by naturalproductman on February 20, 2012

Han-Dong Sun and co-workers from the Kunming Institute of Botany have reported in Organic Letters on the isolation of schilancitrilactones A-C.

schilancitrilactones A-C

OL paper

Posted in Diseases, HIV, Lactones, Nortriterpenoids, Seven-Membered Rings | Leave a Comment »

Chaxine A synthesis

Posted by naturalproductman on January 24, 2012

Arata Yajima and co-workers from the Tokyo University of Agriculture have reported in Tetrahedron on the synthesis of chaxine.

Wittig

Tetrahedron paper

Posted in Horner-Wadsworth-Emmons olefination, Lactones, Methodology, Named Reactions, Ring forming, Total Synthesis | Leave a Comment »

Okilactomycin synthesis

Posted by naturalproductman on January 24, 2012

Thomas Hoye and colleague at the University of Minnesota have reported in Organic Letters on a racemic synthesis of okilactomycin from an intramolecular Diels-Alder.

okilactomycin

OL paper

Posted in Cascade Reactions, Cycloaddition, Diels-Alder, Lactones, Macrocycles, Methodology, Named Reactions, Pericyclic reactions | Leave a Comment »

Artemisinin chemistry

Posted by naturalproductman on January 17, 2012

Giancarlo Marconi and co-workers have reported in Tetrahedron Letters on a reduction of artemisinin, an antimalarial compound, to break down the peroxide bond and open the ring.

artemisinin

TL paper

Posted in Diseases, Lactones, Malaria, Mechanistic, Sesquiterpenes | Leave a Comment »

Rumphellaone A synthesis

Posted by naturalproductman on January 11, 2012

Shigefumi Kuwahara and co-workers from Tohoku University have reported in Tetrahedron Letters on the synthesis of rumphellaone A.  They accessed the four membered ring from a base promoted intramolecular epoxide ring opening.

cyclobutane

TL paper

Posted in Cascade Reactions, Lactones, Methodology, Ring forming, Ring Opening | Leave a Comment »

Biyoulactones A-C

Posted by naturalproductman on September 18, 2011

Jun’ichi Kobayashi and co-workers from Hokkaido University have reported in Organic Letters on the isolation of pentacyclic meroterpenoids dubbed biyoulactones A-C.

lactones

OL paper

Posted in Lactones, Meroterpenoids | Leave a Comment »

 
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