Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘Meroterpenoids’ Category

Anditomin biosynthesis

Posted by naturalproductman on October 4, 2014

Ikuro Abe and co-workers from the University of Tokyo have reported in JACS on a biosynthetic study of anditomin.

biosynthesis

JACS paper

Posted in Biosynthesis, Meroterpenoids | Leave a Comment »

Multi-component approach to guajadial B

Posted by naturalproductman on November 21, 2012

Looking at this molecule, one would never think that you can mix three things, a penta-substituted benzene ring, benzaldehyde and humulene, and obtain the final compound, guajadial! Ji-Kai Liu and co-workers at the Kunming Institute of Botany did such a thing!

MCC
OL paper

Posted in Biosynthesis, Cascade Reactions, Meroterpenoids, Methodology, Multi-Component Coupling, One pot, Total Synthesis | Leave a Comment »

Aureol from sclareolide

Posted by naturalproductman on September 7, 2012

Jonathan George and co-workers at the University of Adeleide in Australia have reported in Organic Letters on the synthesis of aureol from sclareolide.

sclareolide to aureol

OL paper

Posted in Meroterpenoids, Methodology, Total Synthesis | Leave a Comment »

Austinol and dehydroaustinol

Posted by naturalproductman on February 29, 2012

Clay Wang and co-workers at USC have reported in JACS on the biosynthesis determination of two meroterpenoids.
meroterpenoids

JACS paper

Posted in Meroterpenoids | 1 Comment »

Scabellones

Posted by naturalproductman on October 15, 2011

Brent Copp and co-workers from the University of Auckland have reported in the Journal of Organic Chemistry on the isolation of some bioactive compounds dubbed scabellones.

scabellones

JOC paper

Posted in Anti-inflammatory, Diseases, Malaria, Meroterpenoids | Leave a Comment »

Biyoulactones A-C

Posted by naturalproductman on September 18, 2011

Jun’ichi Kobayashi and co-workers from Hokkaido University have reported in Organic Letters on the isolation of pentacyclic meroterpenoids dubbed biyoulactones A-C.

lactones

OL paper

Posted in Lactones, Meroterpenoids | Leave a Comment »

Cytosporolides

Posted by naturalproductman on June 15, 2010

Yongsheng Che and co-workers at the Chinese Academy of Sciences have published in Organic Letters on the isolation of meroterpenoids.

cytosporolides

OL paper

Posted in Meroterpenoids, Peroxides | Leave a Comment »

Liphagal Synthesis

Posted by naturalproductman on June 8, 2010

We’ve previously seen a synthesis of liphagal but here’s another approach to synthesize the seven membered ring from a similar diol precursor – however, the one found here reported by Enrique Alvarez-Manzaneda and co-workers at the Universidad de Granada combines a benzyl deprotection and cationic ring expansion in one step.

liphagal

OL paper

Posted in Cascade Reactions, Meroterpenoids, Methodology, Ring expansion, Seven-Membered Rings | Leave a Comment »

 
Follow

Get every new post delivered to your Inbox.

Join 72 other followers