Looking at this molecule, one would never think that you can mix three things, a penta-substituted benzene ring, benzaldehyde and humulene, and obtain the final compound, guajadial! Ji-Kai Liu and co-workers at the Kunming Institute of Botany did such a thing!
Archive for the ‘Meroterpenoids’ Category
Posted by naturalproductman on November 21, 2012
Posted by naturalproductman on September 7, 2012
Jonathan George and co-workers at the University of Adeleide in Australia have reported in Organic Letters on the synthesis of aureol from sclareolide.
Posted by naturalproductman on February 29, 2012
Clay Wang and co-workers at USC have reported in JACS on the biosynthesis determination of two meroterpenoids.
Posted by naturalproductman on October 15, 2011
Brent Copp and co-workers from the University of Auckland have reported in the Journal of Organic Chemistry on the isolation of some bioactive compounds dubbed scabellones.
Posted by naturalproductman on September 18, 2011
Jun’ichi Kobayashi and co-workers from Hokkaido University have reported in Organic Letters on the isolation of pentacyclic meroterpenoids dubbed biyoulactones A-C.
Posted by naturalproductman on June 15, 2010
Yongsheng Che and co-workers at the Chinese Academy of Sciences have published in Organic Letters on the isolation of meroterpenoids.
Posted by naturalproductman on June 8, 2010
We’ve previously seen a synthesis of liphagal but here’s another approach to synthesize the seven membered ring from a similar diol precursor – however, the one found here reported by Enrique Alvarez-Manzaneda and co-workers at the Universidad de Granada combines a benzyl deprotection and cationic ring expansion in one step.