Naturalproductman’s Blog

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Archive for the ‘Methodology’ Category

Dimerization, electrochemically

Posted by naturalproductman on April 18, 2014

Phil Baran and co-workers reported in JACS on a synthesis of dixiamycin via electrochemical dimerization. I usually think of Kevin Moeller from Washington University in St. Louis when I see electrochemical reactions.

JACS paper

Posted in Dimer, Electrochemical, Indoles, Methodology, Total Synthesis | Leave a Comment »

Ni-catalyzed C-B bond from C-N bond

Posted by naturalproductman on April 4, 2014

Naoto Chatani and co-workers from Osaka University have reported in JACS on a useful transformation of a reductive cleavage of a C-N bond to form C-B and C-H bonds.

Ni

JACS paper

Posted in C-X Bond Breaking, Methodology, Nickel, Transition Metal | Leave a Comment »

Power of enzymes

Posted by naturalproductman on March 30, 2014

Kenji Watanabe and co-workers at Shizuoka University have reported in Chembiochem on the formation of dimeric diketopiperazine alkaloids from a cytochrome P450.

 

Chembiochem paper

Posted in Alkaloids, Cascade Reactions, Dimer, Methodology, Radical Chemistry | Leave a Comment »

Posted by naturalproductman on March 28, 2014

Hideko Koshima and co-workers from Ehime University have reported in JOC on an asymmetric photocyclization of crystals to form chiral cyclobutenols using a chiral counterion.

photocyclization

JOC paper

Posted in Asymmetric, Crystal Structure, Methodology | Leave a Comment »

Kendomycin synthesis

Posted by naturalproductman on March 14, 2014

Hirokazu Arimoto and co-workers from Tohoku University have reported in ACIE on the synthesis of kendomycin.

kendomycin

ACIE paper

Posted in Methodology, Named Reactions, Palladium, Total Synthesis, Transition Metal, Tsuji-Trost | Leave a Comment »

Omaezallene

Posted by naturalproductman on March 14, 2014

Tatsufumi Okino and co-workers from Hokkaido University have reported in ACIE on the synthesis of omaezallene.

omaezallene

ACIE paper

Posted in Allenes, Asymmetric, Methodology, Total Synthesis | Leave a Comment »

Rubromycin synthesis

Posted by naturalproductman on March 14, 2014

Hans-Ulrich Leissig and co-workers at Freie Universitat Berlin have reported in ACIE on the synthesis of rubromycin.

rubromycin

ACIE paper

Posted in Methodology, Polyketides, Total Synthesis | Leave a Comment »

Mandelalide A synthesis

Posted by naturalproductman on March 14, 2014

Furstner and co-workers published in ACIE on the synthesis of mandelalide A, a macrolide found in South Africa. I wonder if this compound was named after Nelson Mandela.

mandelalide

ACIE paper

Posted in Macrolides, Methodology, Total Synthesis | Leave a Comment »

C-H activation methodology

Posted by naturalproductman on March 13, 2014

How crazy is it that one research group publishes in Nature and Science in the SAME week?

 

Science paper

 

Nature paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

Frondosins A and B syntheses

Posted by naturalproductman on March 10, 2014

Dennis Wright and co-workers from the University of Connecticut have reported in JACS on the syntheses of frondosins A and B.

frondosin

JACS paper

Posted in Asymmetric, Methodology, Sesquiterpenoids, Total Synthesis | Leave a Comment »

 
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