Chiral allene synthesis

Doug Frantz and co-workers at UT San Antonio have reported in JACS on a palladium catalyzed asymmetric approach to synthesizing axially chiral allenes through beta-hydride elimination.

JACS paper

Phosphine catalyzed C-N bond formation

Greg Fu and co-workers reported on a C2-symmetric phosphine catalyst to

ACIE paper

pyridines from allenes

Andrei Yudin and co-workers from the University of Toronto have reported in OL on the synthesis of pyridines from allenes.

OL paper

Jiadifenin synthesis

Hongbin Zhai and co-workers at SIOC have reported in ACIE on the synthesis of jiadifenin.  The key [2+2] installed the methyl ester substituent.

ACIE paper

Lactone and allene radical cyclization

David Procter and co-workers from the University of Manchester have reported in JACS on a SmI2-mediated radical cyclization of a lactone bearing an allene to form a 5,7-bicyclic ring system.

JACS paper

Bi-mediated [3+2]

Elisabet Dunac and co-workers from CNRS have reported in Organic Letters on a Bi(OTf)3 mediated [3+2] between an allene and aryl group.

OL paper

Ferrier type cascade

Joseph Kim and co-workers at Sanofi have reported in Tetrahedron Letters on a Ferrier type reaction.

TL paper

Allenoates using NHCs

Jianwei Sun and co-workers at Hong Kong University of Science and Technology have reported in Organic Letters on a carbene catalyzed formation of allenoates.

OL paper

Fucoxanthin synthesis

Shigeo Katsumara and co-workers at Kwansei Gakuin University have reported in Organic Letters on the synthesis of fucoxanthin, an allene containing compound that almost looks like an oxygenated form of beta-carotene.

OL paper

Allenyl azide cyclization

Ken Feldman and colleague at Penn State have reported in Organic Letters on an allenyl azide cycloaddition approach to synthesize meloscine.

OL paper