Naturalproductman’s Blog

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Archive for the ‘Asymmetric’ Category

Ileabethoxazole synthesis

Posted by naturalproductman on June 7, 2014

David Williams and colleague have reported in JACS on the synthesis of ileabethoxazole.

JACS paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Total Synthesis | Leave a Comment »

Silylation of C-H bonds

Posted by naturalproductman on May 6, 2014

I like this silylation of a C-H bond using an iridium catalyst. Very interesting from the lab of John Hartwig at Berkeley.

Ir

JACS paper

Posted in Asymmetric, C-H activation, Iridium, Methodology, Transition Metal | Leave a Comment »

Access to axially chiral compounds

Posted by naturalproductman on May 2, 2014

Scott Miller and co-workers published in Nature on the bromination of a benzamide using a peptide derived catalyst.

 

Nature paper

Posted in Asymmetric, Axial Chirality, Methodology | Leave a Comment »

Asymmetric [2+2]

Posted by naturalproductman on April 25, 2014

Tehshik Yoon and co-workers published in Science on an enantioselective [2+2] reaction.

Science paper

Posted in Asymmetric, Cycloaddition, Light Mediated, Methodology, Pericyclic reactions, [2+2] | Leave a Comment »

Posted by naturalproductman on March 28, 2014

Hideko Koshima and co-workers from Ehime University have reported in JOC on an asymmetric photocyclization of crystals to form chiral cyclobutenols using a chiral counterion.

photocyclization

JOC paper

Posted in Asymmetric, Crystal Structure, Methodology | Leave a Comment »

Omaezallene

Posted by naturalproductman on March 14, 2014

Tatsufumi Okino and co-workers from Hokkaido University have reported in ACIE on the synthesis of omaezallene.

omaezallene

ACIE paper

Posted in Allenes, Asymmetric, Methodology, Total Synthesis | Leave a Comment »

Frondosins A and B syntheses

Posted by naturalproductman on March 10, 2014

Dennis Wright and co-workers from the University of Connecticut have reported in JACS on the syntheses of frondosins A and B.

frondosin

JACS paper

Posted in Asymmetric, Methodology, Sesquiterpenoids, Total Synthesis | Leave a Comment »

Lyconadins A and C syntheses

Posted by naturalproductman on March 10, 2014

Mingji Dai and co-workers from Purdue have reported in ACIE on the syntheses of lyconadins A and C.

lyconadins A and C

ACIE paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Posted by naturalproductman on March 7, 2014

Tsutomu Katsuki and co-workers at Kyushu University have reported on a ruthenium catalyzed kinetic resolution of racemic secondary alcohols via oxidation.

ruthenium

ACIE paper

Posted in Asymmetric, Kinetic resolution, Methodology, Ruthenium, Transition Metal | Leave a Comment »

17-Deoxyprovidencin synthesis

Posted by naturalproductman on March 7, 2014

Johann Mulzer and co-workers have reported in ACIE on the synthesis of 17-deoxyprovidencin.

17-deoxyprovidencin
ACIE paper

Posted in Asymmetric, Light Mediated, Methodology, Total Synthesis | Leave a Comment »

 
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