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Archive for the ‘Cascade Reactions’ Category

multiple reactions back to back (to back) in one go

Diyne desymmetrization

Posted by naturalproductman on May 21, 2013

Ulrich Hennecke and co-workers at the Universitat Munster have reported in JAC on a desymmetrization of a diyne.

Diyne

JACS paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

Transtaganolide syntheses

Posted by naturalproductman on May 17, 2013

Brian Stoltz and co-workers have reported in ACIE on the syntheses of transtaganolides through an Ireland-Claisen rearrangement/Diels-Alder cascade.

ICR/DA

ACIE paper

Posted in Asymmetric, Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Sesquiterpenes, Total Synthesis | Leave a Comment »

Oxazoles to pyridines

Posted by naturalproductman on May 7, 2013

Pierre Yves-Renard and co-workers from CNRS have reported in Organic Letters on an interesting synthesis of pyridines.

pyridines

OL paper

Posted in Cascade Reactions, Mechanistic, Methodology | Leave a Comment »

Triazole annulation

Posted by naturalproductman on May 7, 2013

Huw Davies and colleague from Emory University have reported in JACS on an indole annulation using a triazole.
indole

JACS paper

Posted in Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

Rh-cascade

Posted by naturalproductman on April 22, 2013

Ken Tanaka and co-workers at the Tokyo University of Agriculture and Technology have reported in Org Lett on a rhodium catalyzed cascade reaction to yield substituted cyclopentanones.

rh

OL paper

Posted in Cascade Reactions, Claisen rearrangement, Methodology, Named Reactions, Rhodium, Transition Metal | Leave a Comment »

Vinocrine synthesis

Posted by naturalproductman on April 22, 2013

David Macmillan and colleague have reported in JACS on a synthesis of vinocrine.

vinocrine

JACS paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Methodology | Leave a Comment »

Towards PF-1018

Posted by naturalproductman on April 2, 2013

Dirk Trauner and co-workers at have reported in Organic Letters on a Stille-Diels Alder cascade approach towards PF-1018.

PF-1018

OL paper

Posted in Cascade Reactions, cross coupling, Diels-Alder, Methodology, Named Reactions, Stille | Leave a Comment »

Asymmetric aminoboration of alkenes

Posted by naturalproductman on March 20, 2013

Masahiro Miura and co-workers from Osaka University have reported in JACS on an olefin difunctionalization.

olefin

JACS paper

Posted in Asymmetric, Cascade Reactions, Copper, Methodology, Transition Metal | Leave a Comment »

Triyne to aromatic ring

Posted by naturalproductman on March 15, 2013

Daesung Lee and co-workers at the University of Illinois in Chicago have reported in JACS on a silver promoted cascade involving a C-H insertion from a silver catalyzed aryne formation.

aryne

JACS paper

Posted in Cascade Reactions, Methodology, Silver, Transition Metal | Leave a Comment »

Iron catalyzed [2+2]

Posted by naturalproductman on March 15, 2013

Paul Chirik and co-workers from Princeton have reported in JACS on a mechanistic study of an iron catalyzed [2+2].

iron

JACS paper

Posted in Cascade Reactions, Mechanistic, Methodology | Leave a Comment »

 
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