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Archive for the ‘Cascade Reactions’ Category

multiple reactions back to back (to back) in one go

Power of enzymes

Posted by naturalproductman on March 30, 2014

Kenji Watanabe and co-workers at Shizuoka University have reported in Chembiochem on the formation of dimeric diketopiperazine alkaloids from a cytochrome P450.

 

Chembiochem paper

Posted in Alkaloids, Cascade Reactions, Dimer, Methodology, Radical Chemistry | Leave a Comment »

Lyconadins A and C syntheses

Posted by naturalproductman on March 10, 2014

Mingji Dai and co-workers from Purdue have reported in ACIE on the syntheses of lyconadins A and C.

lyconadins A and C

ACIE paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Gold cyclization

Posted by naturalproductman on March 7, 2014

Stephen Hashmi and co-workers from Ruprecht-Karls-Universität Heidelberg have reported in ACIE on a gold catalyzed cyclization of terminal alkynes.

gold

ACIE paper

Posted in Cascade Reactions, Gold, Methodology, Transition Metal | Leave a Comment »

Ruthenium cascade cyclization

Posted by naturalproductman on March 7, 2014

Yoshihiko Yamamoto and co-workers from Nagoya University have reported on a ruthenium catalyzed hydrogenative cyclization to access dihydrocoumarins.
ruthenium

OL paper

Posted in Cascade Reactions, Diastereoselective, Methodology, Ruthenium, Transition Metal | Leave a Comment »

Hydroacylation of 1,3-dienes

Posted by naturalproductman on March 7, 2014

Vy Dong and co-workers have reported in JACS on a cobalt mediated hydroacylation.

hydroacylation

JACS paper

Posted in Cascade Reactions, Cobalt, Methodology, Transition Metal | Leave a Comment »

Benzyne chemistry for tubingensin A

Posted by naturalproductman on February 19, 2014

Neil Garg and co-workers have reported in JACS on the synthesis of tubingensin A. An interesting [2+2] reaction occurred between a benzyne and an enolate.

2+2

JACS paper

Posted in Alkaloids, benzyne, Cascade Reactions, Methodology | Leave a Comment »

Gold catalyzed sigmatropic rearrangement

Posted by naturalproductman on January 20, 2014

Chepuri Ramana and colleague at CSIR have reported in Chem Comm on a gold catalyzed rearrangement of allenyl ethers.

rearrangement

Chem Comm paper

Posted in Allenes, Cascade Reactions, Gold, Methodology, Transition Metal | Leave a Comment »

Lundurine synthesis

Posted by naturalproductman on January 17, 2014

Atsushi Nishida and co-workers from Chiba University have reported in Org Lett on the synthesis of lundurine.

lundurine

OL paper

Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Bischler–Napieralski-Type Cyclization

Posted by naturalproductman on January 13, 2014

Masaya Nakata and co-workers from Keio University have reported in Org Lett on a Bischler-Napieralski type reaction to form isoindolinones.

FC

OL paper

Posted in Bischler-Napieralski reaction, Cascade Reactions, Methodology, Named Reactions | 1 Comment »

BINOL + SbCl5

Posted by naturalproductman on December 30, 2013

EJ Corey and co-workers reported in JACS on an antimonate catalyzed cation pi-cyclization.

Sb

JACS paper

Posted in Cascade Reactions, Methodology | Leave a Comment »

 
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