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Archive for the ‘Cascade Reactions’ Category

multiple reactions back to back (to back) in one go

Asymmetric metathesis

Posted by naturalproductman on September 8, 2014

Grubbs and colleagues have reported in JACS on their studies with asymmetric ring closing metathesis.

asymmetric

JACS paper

Posted in Asymmetric, Cascade Reactions, Metathesis, Methodology, Ring Opening | 1 Comment »

Towards plumarellide

Posted by naturalproductman on August 31, 2014

Gerald Pattenden and co-workers from the University of Nottingham in the UK have reported in Tetrahedron on a [4+2] approach to plumarellide.

4+2
Tetrahedron paper

Posted in Cascade Reactions, Methodology | 2 Comments »

Oxepanes via Ferrier

Posted by naturalproductman on August 31, 2014

Srinivasan Chandrasekaran and co-workers at the Indian Institute of Science have reported in Tetrahedron on a Ferrier rearrangement to form oxepanes.

 

Ferrier

Tetrahedron paper

Posted in Cascade Reactions, Ferrier, Methodology, Named Reactions, Ring expansion, Ring Opening | Leave a Comment »

Basiliolide B synthesis

Posted by naturalproductman on August 30, 2014

Chi-Sing Lee and co-workers at Shen Zhen University have reported in ACIE on the synthesis of basioli
basiliolide B

ACIE paper

Posted in Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Ring contraction cascade

Posted by naturalproductman on August 30, 2014

Kavirayani R. Prasad and colleague at Indian Institute of Science have reported in ACIE on a ring contraction-ring expansion cascade reaction.

ring contraction

ACIE paper

Posted in Cascade Reactions, Methodology, Triquinanes | Leave a Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | 1 Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | Leave a Comment »

Breaking benzene

Posted by naturalproductman on August 28, 2014

Petr Beier and co-workers from the Academy of the Sciences of the Czech Republic have reported in JOC on an interesting reaction involving hydrogen peroxide, and an SF5-phenol to afford a muconolactone derivative.

BV
JOC paper

Posted in Cascade Reactions, Mechanistic, Methodology, Named Reactions | Leave a Comment »

Stereospecific Aggarwal boronate rearrangement

Posted by naturalproductman on August 28, 2014

Chris Senanayake and co-workers from Boehringer Ingelheim have reported in Organic Letters on an interesting transformation involving a lithiated carbamate and a boronate.

boron

OL paper

Posted in Cascade Reactions, Methodology, Named Reactions | Leave a Comment »

Rearrange to more complexity

Posted by naturalproductman on July 27, 2014

Paul Hergenrother and co-workers from UIUC have reported in ACIE on an interesting rearrangement to form fenestrane ring systems.

cyclopropane

ACIE paper

Posted in Antibiotics, Cascade Reactions, Mechanistic, Methodology | Leave a Comment »

 
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