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Archive for the ‘Conjugate Additions’ Category

Carboboration, organocatalytically

Posted by naturalproductman on July 27, 2014

Masaya Sawamura and co-workers at Hokkaido University have reported in JACS on a carboboration of alkynoates.

carboboration

JACS paper

Posted in Conjugate Additions, Methodology, Organocatalytic | Leave a Comment »

1,4-Reduction with DIBAL

Posted by naturalproductman on December 21, 2011

Yikang Wu and co-workers from the Chinese Academy of Sciences have reported in Tetrahedron on the use of DIBAL to reduce alpha,beta-unsaturated oxazolidin-2-ones.

alpha,beta

Tetrahedron paper

Posted in Conjugate Additions, Copper, Methodology, Transition Metal | Leave a Comment »

Stenine synthesis

Posted by naturalproductman on December 19, 2011

Hongbin Zhang and co-workers at Yunnan University have reported in ACIEE on their synthesis of stenine.

stenine

ACIEE paper

Posted in Alkaloids, Cascade Reactions, Conjugate Additions, Methodology, Michael, Named Reactions | Leave a Comment »

Subincanadine C synthesis

Posted by naturalproductman on October 4, 2011

Hongbin Zhai and co-workers from Shanghai Institute of Organic Chemistry have reported in Organic Letters on the synthesis of subincanadine C.

alkaloid

OL paper

Posted in Alkaloids, Cascade Reactions, Conjugate Additions, Methodology, Michael, Named Reactions, Nickel, Transition Metal | Leave a Comment »

Organocatalytic oxy-Michael

Posted by naturalproductman on September 30, 2011

Seirjiro Matsubara and colleague at Kyoto University have reported in JACS on an organocatalytic oxy-Michael reaction.

intramolecular

JACS paper

Posted in Asymmetric, Conjugate Additions, Methodology, Michael, Named Reactions, Organocatalytic | Leave a Comment »

Aplyviolene synthesis

Posted by naturalproductman on September 26, 2011

Larry Overman and colleague have reported in JACS on a total synthesis of aplyviolene.  Surprisingly, the bromide in the alpha-bromo enone Michael acceptor substrate did not get displaced.

aplyviolene

JACS paper

Posted in Asymmetric, Cascade Reactions, Conjugate Additions, Diterpene, Methodology, Michael, Named Reactions, Total Synthesis | Leave a Comment »

Nazarov cyclization via conjugate addition

Posted by naturalproductman on July 26, 2011

Alison Frontier and co-workers at the University of Rochester have reported in JACS on a Nazarov cyclization

Nazarov

JACS paper

Posted in Conjugate Additions, Methodology, Named Reactions, Nazarov cyclization | Leave a Comment »

From cyclohexenone to alkaloid structure

Posted by naturalproductman on May 15, 2011

Feng-Peng Wang and co-workers at Sichuan University have reported in Tetrahedron on an approach to access some alkaloids from a cyclohexenone.

cyclohexenone

Tetrahedron paper

Posted in Alkaloids, Cascade Reactions, Conjugate Additions, Methodology | Leave a Comment »

Buprenorphine from oripavine

Posted by naturalproductman on May 12, 2011

Thomas Hudlicky and co-workers at Brock University have reported in JOC on the total synthesis of buprenorphine from oripavine.

buprenorphine

JOC paper

Posted in Alkaloids, Cascade Reactions, Conjugate Additions, Methodology, Named Reactions, von Braun | Leave a Comment »

Drechslerines A and B from carvone

Posted by naturalproductman on May 12, 2011

Hisahiro Hagiwara and co-workers from Niigata University have reported in Tetrahedron on the synthesis of drechslerines A and B.

sesquiterpenoid

Tetrahedron paper

Posted in Cascade Reactions, Conjugate Additions, Methodology, Palladium, Sesquiterpenoids, Transition Metal | Leave a Comment »

 
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