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Archive for the ‘Hypervalent Iodine’ Category

Hypervalent iodine promoted aryl shift

Posted by naturalproductman on May 10, 2013

Thomas Wirth and co-workers at Cardiff University have reported in ACIE on a hypervalent iodine reagent promoted migration of an aryl group.

iodine

ACIE paper

Posted in Asymmetric, Hypervalent Iodine, Methodology | Leave a Comment »

Trifluoromethylation with hypervalent iodide

Posted by naturalproductman on February 20, 2012

Zhiqiang Weng and co-workers from Fuzhou University have reported in Tetrahedron on the use of a hypervalent iodide to introduce a trifluoromethyl group on the terminal position of an alkyne.

hypervalent iodide

Tetrahedron paper

Posted in Hypervalent Iodine, Methodology | 2 Comments »

Chiral Hypervalent Iodide

Posted by naturalproductman on February 16, 2012

Morifumi Fujita and co-workers at the University of Hyogo have reported in Organic Letters on the use of a chiral hypervalent iodine reagent

hypervalent iodide

OL paper

Posted in Asymmetric, Cascade Reactions, Hypervalent Iodine, Methodology, Polyketides | Leave a Comment »

Oxyamination

Posted by naturalproductman on February 10, 2012

Thomas Wirth and co-worker from Cardiff University have reported in ACIEE on the use of hypervalent iodine to effect an oxyamination.

oxyamination
ACIEE paper

Posted in Hypervalent Iodine, Methodology | Leave a Comment »

Welwitindolinone C syntheses

Posted by naturalproductman on January 11, 2012

The Rawal and Garg groups published in JACS independently on their syntheses of welwitindolinone C back to back…Garg’s group used a deuterium isotope effect to improve the selectivity in the key C-N bond forming reaction.

alkaloid

JACS paper

deuterium

JACS paper

Posted in Alkaloids, C-H activation, Hypervalent Iodine, Methodology, Silver, Transition Metal | Leave a Comment »

Acyloxylation with gold

Posted by naturalproductman on October 31, 2011

Veronique Michelet and co-workers at CNRS have reported in JACS on a gold catalyzed C-H activation process.
gold

JACS paper

Posted in C-H activation, Gold, Hypervalent Iodine, Methodology, Transition Metal | Leave a Comment »

Olefin oxidation with iodosyl benzene

Posted by naturalproductman on October 22, 2011

Jose Barluenga and co-workers from the Universidad de Oviedo have reported in JACS on an iodosyl benzene mediated oxidation of an olefin to afford beta-diazocarbonyl compounds.

copper

JACS paper

Posted in Cascade Reactions, Copper, Hypervalent Iodine, Methodology, Transition Metal | Leave a Comment »

Oxidative Prins-pinacol

Posted by naturalproductman on October 19, 2011

Sylvain Canesi and co-workers at Université du Québec à Montréal have reported in JOC on an oxidative Prins-pinacol approach towards platensimycin.

oxidative
JOC paper

Posted in Cascade Reactions, Hypervalent Iodine, Methodology, Named Reactions, Pinacol rearrangement, Prins | Leave a Comment »

Cycloheptenes using PIFA

Posted by naturalproductman on September 28, 2011

Siegfried Waldvogel and co-workers at the University of Bonn have reported in European JOC on a hypervalent iodine mediated cyclization.

PIFA

European JOC paper

Posted in Cascade Reactions, Hypervalent Iodine, Methodology, Seven-Membered Rings | 1 Comment »

Decursivine via cascade

Posted by naturalproductman on September 18, 2011

Chaozhong Li and co-workers from the University of Science and Technology in China have reported in Organic Letters on their cascade oxidation approach using PIFA (phenyliodine bis(trifluoroacetate)) to access decursivine.

decursivine

OL paper

Posted in Alkaloids, Cascade Reactions, Hypervalent Iodine, Methodology | 1 Comment »

 
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