Archive for the ‘Metathesis’ Category
Posted by naturalproductman on April 23, 2013
Karl-Heinz Altmann and co-workers at have reported in ACIE on the synthesis of WF-1360F.

ACIE paper
Posted in Macrolides, Metathesis, Methodology, Total Synthesis | Leave a Comment »
Posted by naturalproductman on January 17, 2013
Mark Rizzacasa and co-workers from the University of Melbourne have reported in Organic Letters on their formal synthesis of spirangien A.

OL paper
Posted in Iron, Manganese, Metathesis, Methodology, Polyketides, Spiroketals, Transition Metal | Leave a Comment »
Posted by naturalproductman on October 25, 2012
Michael Burkart and James J. La Clair and colleagues at UCSD have reported in Org Lett on the synthesis of

OL paper
Posted in Macrolides, Metathesis, Methodology, Polyketides, Ring forming, Ruthenium, Structural Reassignment, Transition Metal | Leave a Comment »
Posted by naturalproductman on August 6, 2012
Steven Diver and co-workers from the University of Buffalo have reported in Organic Letters on an enyne metathesis reaction.

OL paper
Posted in Cascade Reactions, Metathesis, Methodology | Leave a Comment »
Posted by naturalproductman on May 7, 2012
Kathlynn Parker and colleague have reported in Organic Letters on a formal synthesis of englerin A.

OL paper
Posted in Cascade Reactions, Metathesis, Methodology, Ruthenium, Sesquiterpenoids, Transition Metal | Leave a Comment »
Posted by naturalproductman on May 1, 2012
Dennis Curran and co-workers at the University of Pittsburgh have applied fluorous mixture synthesis to assign the stereochemistry of a macrolide. Fluorous mixture synthesis is a technique where they install fluorinated tag protecting groups on the alcohols where each tag varies by the number of fluorines. They are able to separate the tagged compounds based on the number of flourines on the tags.

JACS paper
Science paper
Posted in Macrolides, Metathesis, Methodology, Ruthenium, Total Synthesis, Transition Metal | Leave a Comment »
Posted by naturalproductman on April 17, 2012
Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of oxyingenol.

ACIE paper
Posted in Diseases, Diterpenoids, HIV, Metathesis, Methodology, Ruthenium, Sigmatropic Rearrangements, Total Synthesis, Transition Metal | Leave a Comment »
Posted by naturalproductman on January 24, 2012
Jared Shaw and co-workers at UC Davis have reported in Synthesis on their approach towards viriditoxin.

Synthesis paper
Posted in Aromatic, C2-Symmetric, Dimer, Metathesis, Methodology, Total Synthesis | Leave a Comment »
Posted by naturalproductman on December 14, 2011
Seunghoon Shin and co-workers at Hanyang University have reported in JACS on a gold catalyzed enyne cross metathesis between propiolic acids and alkenes.

JACS paper
Posted in Cascade Reactions, Computational, DFT, Gold, Mechanistic, Metathesis, Methodology, Transition Metal | Leave a Comment »
Posted by naturalproductman on December 9, 2011
Kozo Shishido and co-workers at the University of Tokushima have reported in Organic Letters on the synthesis of penostatin B relying on a relay ring closing metathesis.

OL paper
Posted in Asymmetric, Cascade Reactions, Metathesis, Methodology, Named Reactions, Pauson-Khand, Total Synthesis | Leave a Comment »