Antonio Echavarren and co-workers from ICIQ in Spain have reported in Org Lett on a gold catalyzed intramolecular [2+2] between an alkene and alkyne.
Posted by naturalproductman on February 21, 2013
John Chisholm and co-workers from Syracuse University have reported in Tetrahderon Letters on an intramolecular approach towards maeocrystal V.
Posted by naturalproductman on November 19, 2012
Peter Wipf and co-workers from University of Pittsburgh have reported in JOC on method for synthesis of 5-hydroxyindoles from furans.
Posted by naturalproductman on November 6, 2012
Danishefsky and colleague have reported in JACS on a racemic synthesis of maeocrystal V.
Posted by naturalproductman on August 29, 2012
Hongbin Zhai and co-workers at SIOC have reported in ACIE on the synthesis of jiadifenin. The key [2+2] installed the methyl ester substituent.
Posted by naturalproductman on August 23, 2012
Stoltz and colleague have reported in ACIE on the enantioselective syntheses of some sesquiterpenoid biosynthetic precursors. The 5,6-ring system was made from an intramolecular Diels-Alder.
Posted by naturalproductman on August 15, 2012
Sarah Reisman and colleague have reported in Organic Letters on their elegant approach to acutimine via a [2+2] cycloaddition – however, their retro-aldol reaction to open the cyclobutane ring failed.
Posted by naturalproductman on July 3, 2012
Deukjoon Kim (Seoul National University) and Jonathon Burton (University of Oxford) and co-workers have reported in JACS on a synthesis of elatenyne.