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Archive for the ‘Transition Metal’ Category

Reactions involving transition metals

Intermolecular hydroamination

Posted by naturalproductman on October 29, 2014

Stephen Buchwald and colleague have reported in JACS on an asymmetric intermolecular hydroamination reaction. I personally have tried an intermolecular hydroamination using a platinum catalyst, and it failed. This protocol is hopefully a good alternative.

copper

JACS paper

Posted in Copper, Methodology, Transition Metal | Leave a Comment »

Fe-catalyzed cross coupling

Posted by naturalproductman on October 4, 2014

Eiichi Nakamura and co-workers at the University of Tokyo have reported in JACS on an iron catalyzed C-sp2-H to organoboron cross coupling reaction.

boron

JACS paper

Posted in C-H activation, Cascade Reactions, Iron, Methodology, Transition Metal | Leave a Comment »

Allenyl gold complexes

Posted by naturalproductman on September 8, 2014

Concepcion Gimeno and co-workers from ISQCH in Spain have reported in JACS on an allenyl gold complex. I wonder how they would react with electrophiles.

allenyl gold

JACS paper

Posted in Allenes, Gold, Methodology, Transition Metal | Leave a Comment »

Scandium-catalyzed hydroarylation

Posted by naturalproductman on August 30, 2014

Zhaomin Hou and co-workers from RIKEN have reported in JACS on an enantioselective hydroarylation using a scandium complex.
Sc

JACS paper

Posted in C-H activation, Methodology, Scandium, Transition Metal | Leave a Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | 1 Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | Leave a Comment »

C-C bond cleavage with titanium

Posted by naturalproductman on August 28, 2014

Zhaomin Hou and co-workers at RIKEN (Saitama, JP) have reported in Nature on a titanium hydride complex that cleaves carbon-carbon bonds.

 

Nature paper

Posted in C-C Bond Breaking, Methodology, Titanium, Transition Metal | Leave a Comment »

Cyclobutenone ring expansion

Posted by naturalproductman on August 20, 2014

Guangbin Dong and colleague at UT Austin have reported in ACIE on the synthesis of cycloinumakiol through a rhodium catalyzed cascade reaction that forms the tetracyclic ring structure of the compound.

C-C

ACIE paper

Posted in Methodology, One pot, Rhodium, Ring expansion, Ring forming, Ring Opening, Total Synthesis, Transition Metal | Leave a Comment »

Z-selective olefin metathesis

Posted by naturalproductman on August 20, 2014

Robert Grubbs and co-workers have reported in JACS on factors that influence Z-selective olefin metathesis.

Z-selective

JACS paper

Posted in Metathesis, Methodology, Ring forming, Ruthenium, Transition Metal | Leave a Comment »

Electrocyclic ring opening to ketonitrones

Posted by naturalproductman on July 27, 2014

Masahiro Terada and co-workers from Tohoku University have reported in Organic Letters on a copper-catalyzed rearrangement to form alpha,beta-unsaturated ketonitrones.

nitrone

OL paper

Posted in Cascade Reactions, Copper, Electrocyclization, Mechanistic, Methodology, Pericyclic reactions, Transition Metal | Leave a Comment »

 
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