Naturalproductman’s Blog

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Archive for the ‘Copper’ Category

Posted by naturalproductman on September 5, 2013

Masaya Sawamura and co-workers published in ACIE on a copper catalyzed three component coupling between an alkyl borane, tributyltin methoxide, and an alkynoate.

tin

ACIE paper

Posted in Copper, Methodology, Multi-Component Coupling, Transition Metal | Leave a Comment »

Asymmetric aminoboration of alkenes

Posted by naturalproductman on March 20, 2013

Masahiro Miura and co-workers from Osaka University have reported in JACS on an olefin difunctionalization.

olefin

JACS paper

Posted in Asymmetric, Cascade Reactions, Copper, Methodology, Transition Metal | Leave a Comment »

Desaturation

Posted by naturalproductman on February 21, 2013

C-H bond activation is popular because you can convert alkanes into alcohols – looks like a desaturase reaction where alkanes turn into alkenes is going to be up and coming in popularity soon. Pedro Perez and co-workers at CIQSO in Spain have reported in JACS on a copper catalyst that converted alkanes to alkenes.

 

JACS paper

Posted in C-H activation, Cascade Reactions, Copper, Dehydrogenation, Methodology, Transition Metal | Leave a Comment »

Aziridinone oxidant

Posted by naturalproductman on February 20, 2013

Yian Shi and co-workers have published in OL on a copper catalyzed oxidation of alcohols using an aziridinone oxidant.

copper

OL paper

Posted in Cascade Reactions, Copper, Methodology, Transition Metal | Leave a Comment »

Thiophenes from Simmons-Smith

Posted by naturalproductman on November 30, 2012

Kanchugarakoppal Rangappa and co-workers at the University of Mysore in India have reported in Tetrahedron Letters on the synthesis of thiophenes using a Simmons-Smith reagent.

thiophene

TL paper

Posted in Cascade Reactions, Copper, Methodology, Named Reagents, Simmons-Smith, Transition Metal, Zinc | Leave a Comment »

1,4-conjugate addition in water

Posted by naturalproductman on November 28, 2012

Bruce Lipshutz and co-workers have reported in JACS on a organocuprate Michael addition in WATER.

Cu

JACS paper

Posted in Cascade Reactions, Copper, Environmental, Methodology, Transition Metal, Zinc | Leave a Comment »

Ullman with light

Posted by naturalproductman on November 2, 2012

I guess Greg Fu made a statement at Caltech with his Science paper in collaboration with the Jonas Peters group. This Science paper discloses an Ullman reaction (copper mediated aryl iodide and amine coupling) in the presence of light.

 

Science paper

Posted in Copper, cross coupling, Light Mediated, Methodology, Transition Metal, Ullmann | Leave a Comment »

Halogen migration

Posted by naturalproductman on September 18, 2012

Jennifer Schomaker and co-workers from the University of Wisconsin have reported in JACS on a copper catalyzed 1,3-halogen migration reaction.

 

JACS paper

Posted in Cascade Reactions, Copper, Methodology, Transition Metal | Leave a Comment »

Copper catalyzed fluorination

Posted by naturalproductman on September 17, 2012

Thomas Lectka and co-workers at Johns Hopkins University have reported in ACIE on a copper catalyzed fluorination process.

copper

ACIE paper

Posted in C-H activation, Copper, Methodology, Transition Metal | Leave a Comment »

Copper Catalyzed C-N Bond Formation

Posted by naturalproductman on July 31, 2012

Nello Mainolfi and co-workers at Novartis have reported in Chemical Science on a copper catalyzed decarboxylative C-N bond forming reaction.

decarboxylative

Chemical Science paper

Posted in Copper, Methodology, Transition Metal | Leave a Comment »

 
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