Theodore Betley and co-worker have reported in Science on an iron catalyzed C-H amination.
Archive for the ‘Iron’ Category
Fe-catalyzed C-H amination
Posted by naturalproductman on May 6, 2013
Posted in C-H activation, Iron, Methodology, Transition Metal | Leave a Comment »
Mitsunobu with a catalytic twist
Posted by naturalproductman on March 8, 2013
Hiroyuki Ishibashi and co-workers at Kanazawa University have reported in ACIE on a Mitsunobu reaction where they use an iron catalyst and oxygen to regenerate the active azo reagent.

Posted in Catalytic, Iron, Methodology, Mitsunobu, Named Reactions, Transition Metal | Leave a Comment »
Aminohydroxylation of alkenes
Posted by naturalproductman on February 27, 2013
Hao Xu and co-workers at Georgia State University have reported in JACS on an iron catalyzed aminohydroxylation reaction.

Posted in Cascade Reactions, Iron, Methodology, Transition Metal | Leave a Comment »
Spirangien A synthesis
Posted by naturalproductman on January 17, 2013
Mark Rizzacasa and co-workers from the University of Melbourne have reported in Organic Letters on their formal synthesis of spirangien A.

Posted in Iron, Manganese, Metathesis, Methodology, Polyketides, Spiroketals, Transition Metal | Leave a Comment »
ortho-Naphthoquinone methides
Posted by naturalproductman on December 29, 2012
Hironao Sajiki and co-workers from Gifu Pharmaceutical University have reported in ACIE on a generation of naphthoquinone methides using an iron catalyst.
Posted in Cascade Reactions, Diels-Alder, Iron, Methodology, Named Reactions, Transition Metal | Leave a Comment »
Fluorination of alkenes
Posted by naturalproductman on August 8, 2012
Dale Boger and colleague have reported in JACS on process involving the fluorination of an alkene using super stoichiometric amounts of iron and excess sodium borohydride.

Posted in Cascade Reactions, Iron, Mechanistic, Methodology, Transition Metal | Leave a Comment »
Nitroso-ene reaction followed by reduction
Posted by naturalproductman on August 6, 2012
Radhey Srivastava and co-workers at the University of Louisiana have reported in JOC on a nitroso-ene reaction.

Posted in Cascade Reactions, Iron, Mechanistic, Methodology, Pericyclic reactions, Sigmatropic Rearrangements, Transition Metal | Leave a Comment »
Vinblastine analogs
Posted by naturalproductman on February 29, 2012
Dale Boger and colleagues have reported in Organic Letters on the functionalization of alkenes using iron. When I first saw vinblastine I thought of Dale Boger because he does so much work on this compound and it looks like I was thinking the right person.

Posted in Alkaloids, Iron, Methodology, Transition Metal, Unnatural Products | Leave a Comment »
Trifluoromethylation of vinyltrifluoroborates
Posted by naturalproductman on February 21, 2012
Buchwald and co-workers have reported in ACIEE on an iron catalyzed trifluoromethylation of vinyltrifluoroborates.

Posted in Cascade Reactions, cross coupling, Iron, Methodology, Transition Metal | Leave a Comment »
Evidence of iron-oxo
Posted by naturalproductman on October 13, 2011
Miquel Costas and co-workers at Universitat de Girona in Spain have reported in Nature Chemistry on the observation of an iron-oxo complex using mass spectrometry.

Posted in Computational, DFT, Iron, Mass Spectrometry, Mechanistic, Methodology, Transition Metal | Leave a Comment »
