Spirangien A synthesis

Mark Rizzacasa and co-workers from the University of Melbourne have reported in Organic Letters on their formal synthesis of spirangien A.

OL paper

Manganese catalyzed fluorination

John Groves and co-workers have reported in Science on a manganese promoted fluorination process of aliphatics.

 

Science paper

Selective C-H activation process

Konstantin Bryliakov and co-workers at the Boreskov Institute of Catalysis in Russia have reported in Organic Letters on a selective C-H activation process.

OL paper

Fusarisetin A synthesis

Shuanhu Gao and co-workers at East China Normal University have reported in ACIE on the synthesis of fusarisetin through an intramolecular Diels-Alder in addition to an interesting manganese catalyzed radical cyclization to form an endoperoxide that is transformed to the tetrahydrofuran ring.

ACIE paper

Chloroacetonylation

Metin Balci and co-workers at Middle East Technical University in Turkey have reported in Tetrahedron Letters on a manganese acetate promoted chloroacetonylation across an olefin.

TL paper

Dimanganese hydroxylase

Yi Tang and co-workers from UCLA have reported in JACS on the characterization of a hydroxylase enzyme made up of two manganese metal centers responsible for catalysis.

JACS paper

Ageliferin synthesis

Chuo Chen and colleagues at UT Southwestern have reported in JACS on their synthesis of ageliferin, featuring a Mn-promoted cascade radical cyclization.

JACS paper

Manganese C-H Activation

Douglas Taber and colleague have reported in JOC on a manganese catalyzed C-H activation process to form one of the rings in (−)-cameroonan-7α-ol.

JOC paper

Mn-Catalyzed Chlorination

John Groves and co-worker at Princeton have published in JACS on a manganese porphyrin mediated C-H chlorination reaction using sodium hypochlorite as the chlorine source.  The yields and regioselectivity are modest for the more complex systems but it’s cool nonetheless.

JACS paper

Synthesis of Ialibinones

Nigel Simpkins and co-worker at the University of Birmingham have published in Tetrahedron Letters on a manganese/copper mediated oxidative cyclization reaction to access ialibinone.

TL paper