Naturalproductman’s Blog

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Archive for the ‘Nickel’ Category

Ni-catalyzed C-B bond from C-N bond

Posted by naturalproductman on April 4, 2014

Naoto Chatani and co-workers from Osaka University have reported in JACS on a useful transformation of a reductive cleavage of a C-N bond to form C-B and C-H bonds.

Ni

JACS paper

Posted in C-X Bond Breaking, Methodology, Nickel, Transition Metal | Leave a Comment »

Ni-catalyzed acyl cross-coupling

Posted by naturalproductman on May 9, 2013

Sarah Reisman and co-workers have reported in JACS on a Ni-catalyzed coupling of an aryl chloride and acyl chloride.

Ni

JACS paper

Posted in Asymmetric, Methodology, Nickel, Transition Metal | Leave a Comment »

Abyssomicin synthesis

Posted by naturalproductman on April 23, 2012

Radomir Saicic and colleague at the University of Belgrade in Serbia have reported in ACIE on the synthesis of atrop-abyssomicin.

abyssomycin

ACIE paper

Posted in Asymmetric, Cascade Reactions, Chromium, Methodology, Named Reactions, Nickel, Nozaki-Hiyama-Kishi, Total Synthesis, Transition Metal | Leave a Comment »

NHK coupling asymmetrically

Posted by naturalproductman on March 29, 2012

The Nozaki-Hiyama-Kishi coupling couples an a R-halide group with an aldehyde.  Kishi and co-workers have reported on a catalytic, asymmetric version in JACS recently.
NHK

JACS paper

Posted in Asymmetric, Chromium, cross coupling, Methodology, Named Reactions, Nickel, Nozaki-Hiyama-Kishi, Transition Metal | Leave a Comment »

Nickel catalyzed cyclization

Posted by naturalproductman on January 7, 2012

At first look you might think reacting an indole with a three membered ring is reminiscent of Pagenkopf’s or Kerr’s work at the University of Western Ontario where the three membered ring is a cyclopropane – however, here we see that the three membered ring is an epoxide and the catalyst is nickel – so the authors must be different…Junliang Zhang and co-workers at SIOC have reported in Chemical Communications on a nickel catalyzed [3+2] between an epoxide and an indole.
indole

Chem Comm paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Nickel, Transition Metal | Leave a Comment »

2 dienes + 1 alkyne

Posted by naturalproductman on January 4, 2012

Phil Baran and co-workers have reported in JOC on a nickel catalyzed diene-alkyne cooligomerization reaction.

nickel

JOC paper

Posted in Cascade Reactions, Methodology, Multi-Component Coupling, Nickel, Transition Metal | Leave a Comment »

Intermolecular [4+2] approach for pyridines

Posted by naturalproductman on October 21, 2011

Sensuke Ogoshi and co-workers from Osaka University have reported in JACS on a nickel-catalyzed [4+2] approach to access pyridines.

pyridine

JACS paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Nickel, Pericyclic reactions, Transition Metal | Leave a Comment »

Subincanadine C synthesis

Posted by naturalproductman on October 4, 2011

Hongbin Zhai and co-workers from Shanghai Institute of Organic Chemistry have reported in Organic Letters on the synthesis of subincanadine C.

alkaloid

OL paper

Posted in Alkaloids, Cascade Reactions, Conjugate Additions, Methodology, Michael, Named Reactions, Nickel, Transition Metal | Leave a Comment »

Nickel catalyzed double C-H activation

Posted by naturalproductman on September 28, 2011

Janis Louie and colleague have reported in ACIEE on a nickel catalyzed double C-H activation reaction.

C-H

ACIEE paper

Posted in C-H activation, Methodology, Nickel, Transition Metal | Leave a Comment »

Cyclopropane formation via nickel

Posted by naturalproductman on August 19, 2011

Seijiro Matsubara and co-workers at Kyoto University have reported in ACIEE on a nickel catalyzed cyclization between an alkyne and an alpha,beta,gamma,delta-unsaturated (2 alkenes) ketone to form a cyclopropane product.

cyclopropane

ACIEE paper

Posted in Cascade Reactions, Methodology, Nickel, Ring forming, Transition Metal | Leave a Comment »

 
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