Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘Palladium’ Category

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | 1 Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | Leave a Comment »

Pd-catalyzed C-N bond formation

Posted by naturalproductman on June 5, 2014

Matthew Gaunt and co-workers from the University of Cambridge have reported in Nature on a palladium catalyzed intramolecular C-N bond formation from C-H bonds. I am reminded of the ACIE paper from Frances Arnold’s group at Caltech where they used a P450 mutant to do a similar reaction.

 

Nature paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

Macrolactonization towards neopeltolide

Posted by naturalproductman on May 13, 2014

Mingji Dai and co-workers from Purdue have reported in ACIE on alkoxycarbonylative macrocyclization.

Pd

ACIE paper

Posted in Macrolides, Methodology, Palladium, Transition Metal | Leave a Comment »

5-exo-dig vs. 6-endo-dig cyclization

Posted by naturalproductman on April 25, 2014

Hideki Yorimitsu and co-workers from Kyoto University have reported in JACS on a palladium catalyzed cyclization of alkynols. The regioselectivity depends on the ligand used, Xantphos gives 6-membered rings and Xphos gives 5-membered rings.

 

JACS paper

Posted in Cascade Reactions, Methodology, Palladium, Transition Metal | Leave a Comment »

Kendomycin synthesis

Posted by naturalproductman on March 14, 2014

Hirokazu Arimoto and co-workers from Tohoku University have reported in ACIE on the synthesis of kendomycin.

kendomycin

ACIE paper

Posted in Methodology, Named Reactions, Palladium, Total Synthesis, Transition Metal, Tsuji-Trost | Leave a Comment »

C-H activation methodology

Posted by naturalproductman on March 13, 2014

How crazy is it that one research group publishes in Nature and Science in the SAME week?

 

Science paper

 

Nature paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

Silyl Heck reaction

Posted by naturalproductman on August 30, 2013

Donald Watson and colleague have reported in JACS on silyl Heck variant.

vinyl silyl ethers

JACS paper

Posted in cross coupling, Heck, Methodology, Palladium, Transition Metal | Leave a Comment »

C-P bond from a C-H bond

Posted by naturalproductman on July 24, 2013

Masahiro Murakami and co-workers have reported in ACIE on a C-P bond formation.

C-H

ACIE paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

C-H activation

Posted by naturalproductman on July 24, 2013

Nobuharu Iwasawa and co-workers at Tokyo Institute of Technology have reported in JACS on a palladium catalyzed CO2 fixation reaction to form coumarins from a vinyl phenol.

coumarin

JACS paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

 
Follow

Get every new post delivered to your Inbox.

Join 73 other followers