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Archive for the ‘Palladium’ Category

Alkyl halides from aryl halides

Posted by naturalproductman on November 8, 2014

Zhenfeng Xi and co-workers from SIOC have reported in ACIE on the transfer of a halogen from an aryl group to an alkyl group.

reductive elimination

ACIE paper

Posted in Mechanistic, Methodology, Palladium, Transition Metal | Leave a Comment »

Pd pi-allyl

Posted by naturalproductman on November 8, 2014

Shu-Li You and co-workers at SIOC have reported in JACS on some mechanistic studies of a Pd pi-allyl chemistry.

pi allyl

JACS paper

Posted in Asymmetric, Mechanistic, Methodology, Named Reactions, Palladium, Transition Metal, Tsuji-Trost | Leave a Comment »

Asymmetric aza-Pinacol rearrangement

Posted by naturalproductman on November 4, 2014

Yong-Gui Zhou and co-workers at SIOC have reported in JACS on an asymmetric aza-Pinacol rearrangement.

asymmetric

JACS paper

Posted in Asymmetric, Aza-Pinacol, Cascade Reactions, Methodology, Named Reactions, Palladium, Ring expansion, Transition Metal | Leave a Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | 1 Comment »

Palladium catalyzed decarboxylative cycloaddition

Posted by naturalproductman on August 30, 2014

Yong Jian Zhang and co-workers at Shanghai Jiao Tong University have reported in ACIE on a palladium catalyzed decarboxylative cycloaddition.

palladium

ACIE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Palladium, Transition Metal | Leave a Comment »

Pd-catalyzed C-N bond formation

Posted by naturalproductman on June 5, 2014

Matthew Gaunt and co-workers from the University of Cambridge have reported in Nature on a palladium catalyzed intramolecular C-N bond formation from C-H bonds. I am reminded of the ACIE paper from Frances Arnold’s group at Caltech where they used a P450 mutant to do a similar reaction.

 

Nature paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

Macrolactonization towards neopeltolide

Posted by naturalproductman on May 13, 2014

Mingji Dai and co-workers from Purdue have reported in ACIE on alkoxycarbonylative macrocyclization.

Pd

ACIE paper

Posted in Macrolides, Methodology, Palladium, Transition Metal | Leave a Comment »

5-exo-dig vs. 6-endo-dig cyclization

Posted by naturalproductman on April 25, 2014

Hideki Yorimitsu and co-workers from Kyoto University have reported in JACS on a palladium catalyzed cyclization of alkynols. The regioselectivity depends on the ligand used, Xantphos gives 6-membered rings and Xphos gives 5-membered rings.

 

JACS paper

Posted in Cascade Reactions, Methodology, Palladium, Transition Metal | Leave a Comment »

Kendomycin synthesis

Posted by naturalproductman on March 14, 2014

Hirokazu Arimoto and co-workers from Tohoku University have reported in ACIE on the synthesis of kendomycin.

kendomycin

ACIE paper

Posted in Methodology, Named Reactions, Palladium, Total Synthesis, Transition Metal, Tsuji-Trost | Leave a Comment »

C-H activation methodology

Posted by naturalproductman on March 13, 2014

How crazy is it that one research group publishes in Nature and Science in the SAME week?

 

Science paper

 

Nature paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | Leave a Comment »

 
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