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Archive for the ‘Claisen condensation’ Category

Ketene cascade

Posted by naturalproductman on September 18, 2011

Anthony Barrett and co-workers at Imperial College have reported in Organic Letters on a cascade reaction that involves the formation of a ketene followed by trapping with an enamine to form pyridinones.

pyridinones

OL paper

Posted in Cascade Reactions, Claisen condensation, Diels-Alder, Methodology, Named Reactions, Transition Metal, Zinc | Leave a Comment »

Reformatsky-Claisen Cascade

Posted by naturalproductman on November 19, 2010

Jeffrey Johnson and co-workers at UNC have published in JACS on a Refoormatzky-Claisen condensation cascade reaction where the second enolate generated opens a beta-lactone.

beta lactone

 

JACS paper

Posted in Cascade Reactions, Claisen condensation, Methodology, Multi-Component Coupling, Named Reactions, Reformatsky, Ring Opening, Transition Metal, Zinc | Leave a Comment »

 
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