Brian Stoltz and co-workers have reported in ACIE on the syntheses of transtaganolides through an Ireland-Claisen rearrangement/Diels-Alder cascade.
Archive for the ‘Claisen rearrangement’ Category
Transtaganolide syntheses
Posted by naturalproductman on May 17, 2013
Posted in Asymmetric, Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Sesquiterpenes, Total Synthesis | Leave a Comment »
Rh-cascade
Posted by naturalproductman on April 22, 2013
Ken Tanaka and co-workers at the Tokyo University of Agriculture and Technology have reported in Org Lett on a rhodium catalyzed cascade reaction to yield substituted cyclopentanones.
Posted in Cascade Reactions, Claisen rearrangement, Methodology, Named Reactions, Rhodium, Transition Metal | Leave a Comment »
Vinigrol synthesis
Posted by naturalproductman on January 19, 2012
Louis Barriault and co-workers at the University of Ottawa have reported in ACIEE on the formal synthesis of vinigrol – I think this makes the number of groups to synthesize this molecule to 2, Baran being the other one.
Posted in Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Total Synthesis | Leave a Comment »
Lysidicin A synthesis from a triple Claisen rearrangement
Posted by naturalproductman on January 17, 2012
Hidenori Watanabe and co-workers at the University of Tokyo have reported in Tetrahedron on the synthesis of lysidicin. The key reaction being a triple Claisen rearrangement that formed three of the aryl carbon bonds from aryl ether linkages.
Posted in Cascade Reactions, Claisen rearrangement, Methodology, Mitsunobu, Named Reactions, Polyketides, Total Synthesis | Leave a Comment »
Saudin synthesis
Posted by naturalproductman on November 21, 2011
Robert Boeckman and co-workers at the University of Rochester have reported in Tetrahedron on the synthesis of saudin.
Posted in Asymmetric, Cascade Reactions, Claisen rearrangement, Methodology, Named Reactions, Terpenes | Leave a Comment »
Transannular Claisen rearrangement
Posted by naturalproductman on October 23, 2011
Donald Craig and co-workers at Imperial College have reported in Organic and Biomolecular Chemistry on a transannular Claisen rearrangement converting a lactone into a cyclobutane.
Posted in Claisen rearrangement, Methodology, Named Reactions, Ring contraction | Leave a Comment »
Daphmanidin synthesis
Posted by naturalproductman on October 11, 2011
Posted in Alkaloids, Cascade Reactions, Claisen rearrangement, Cobalt, Copper, cross coupling, Heck, Methodology, Named Reactions, Palladium, Transition Metal | Leave a Comment »
Alkyne to caged compound
Posted by naturalproductman on June 9, 2011
Qi-Dong You and co-workers from China Pharmaceutical University have reported in Tetrahedron on a diyne compound undergoing a hydrogenation/Claisen/Diels-Alder cascade to afford the caged carbon skeleton of gaudichaudione A and isomorellin.
Posted in Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Palladium, Transition Metal | Leave a Comment »
What happened here?!
Posted by naturalproductman on April 6, 2011
Nuno Maulide and co-workers at Max-Planck-Institut fur Kohlenforschung
Kaiser-Wilhelm-Platz have reported in Chemistry European Journal on an interesting transformation.
Posted in Cascade Reactions, Claisen rearrangement, Mechanistic, Methodology, Named Reactions | Leave a Comment »
Gold Catalyzed Gostelli-Claisen
Posted by naturalproductman on March 23, 2011
Martin Hiersemann and co-workers at Universitat Dortmund have reported in Organic Letters on a gold catalyzed Gosteli-Claisen rearrangement.
Posted in Cascade Reactions, Claisen rearrangement, Gold, Methodology, Named Reactions, Pericyclic reactions, Sigmatropic Rearrangements, Transition Metal | Leave a Comment »
