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Archive for the ‘Diels-Alder’ Category

Claisen-Diels-Alder cascade to spirooliganones A and B

Posted by naturalproductman on July 16, 2014

Rongbiao Tong and co-workers from the Hong Kong University of Science and Technology have reported in Org Lett on a slick reaction to form spirooliganones.

 
spirooliganones

OL paper

Posted in Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Total Synthesis | Leave a Comment »

Bolivianine synthesis

Posted by naturalproductman on June 11, 2013

Bo Liu and co-workers at Sichuan University have reported in JACS on a synthesis of bolivianine using a Diels-Alder cascade for the final key step.

JACS paper

Posted in Diels-Alder, Named Reactions, Total Synthesis | Leave a Comment »

Transtaganolide syntheses

Posted by naturalproductman on May 17, 2013

Brian Stoltz and co-workers have reported in ACIE on the syntheses of transtaganolides through an Ireland-Claisen rearrangement/Diels-Alder cascade.

ICR/DA

ACIE paper

Posted in Asymmetric, Cascade Reactions, Claisen rearrangement, Diels-Alder, Methodology, Named Reactions, Sesquiterpenes, Total Synthesis | Leave a Comment »

Towards PF-1018

Posted by naturalproductman on April 2, 2013

Dirk Trauner and co-workers at have reported in Organic Letters on a Stille-Diels Alder cascade approach towards PF-1018.

PF-1018

OL paper

Posted in Cascade Reactions, cross coupling, Diels-Alder, Methodology, Named Reactions, Stille | Leave a Comment »

Kingianin synthesis

Posted by naturalproductman on March 6, 2013

Michael Sherburn and co-workers from Australian National University have reported in ACIE on the synthesis of kingianins A, D, and F from a poly-yne precursor.  Ledwith-Weitz salt was used to promote a Diels-Alder dimerization.

Diels-Alder

 

ACIE paper

Posted in Cascade Reactions, Diels-Alder, Ledwith-Weitz salt, Methodology, Named Reactions, Total Synthesis | Leave a Comment »

Towards maoecrystal V

Posted by naturalproductman on February 21, 2013

John Chisholm and co-workers from Syracuse University have reported in Tetrahderon Letters on an intramolecular approach towards maeocrystal V.

maoecrystal V

TL paper

Posted in Cycloaddition, Diels-Alder, Methodology, Named Reactions, Pericyclic reactions | Leave a Comment »

Spontaneous Diels-Alder

Posted by naturalproductman on January 31, 2013

Craig Merlic and co-workers from UCLA have reported in Organic Letters on a spontaneous transannular Diels-Alder when they used a palladium catalyzed C-C bond forming strategy.

Diels-Alder

OL paper

Posted in Cascade Reactions, Diels-Alder, Methodology, Named Reactions, Palladium, Transition Metal | Leave a Comment »

Aza-Diels-Alder

Posted by naturalproductman on January 23, 2013

Eric Jacobsen and co-workers have published in JACS on an aza-Diels-Alder. I didn’t know the N. stood for Niels.

 

JACS paper

Posted in Cascade Reactions, Diels-Alder, Methodology, Named Reactions | Leave a Comment »

Calvicularin synthesis

Posted by naturalproductman on January 10, 2013

Christopher Beaudry and co-workers from Oregon State have reported in Organic Letters on a synthesis of cavicularin using a vinyl sulfone for a Diels-Alder substrate.

calvicularin

OL paper

Posted in Aromatic, Cascade Reactions, Diels-Alder, Methodology, Named Reactions, Polyketides | Leave a Comment »

ortho-Naphthoquinone methides

Posted by naturalproductman on December 29, 2012

Hironao Sajiki and co-workers from Gifu Pharmaceutical University have reported in ACIE on a generation of naphthoquinone methides using an iron catalyst.

methides
ACIE paper

Posted in Cascade Reactions, Diels-Alder, Iron, Methodology, Named Reactions, Transition Metal | Leave a Comment »

 
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