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Archive for the ‘Eguchi aza-Wittig’ Category

Circumdatin H Synthesis

Posted by naturalproductman on January 9, 2010

Subhas Bose and co-worker at the Indian Institute of Chemical Technology have recently published in Chemical Communications on the synthesis of circumdatin H, an NADH oxidase inhibitor.  The key reaction was an Eguchi-aza-Wittig reaction to form the carbon nitrogen double bond.

circumdatin H
Synthesis paper

Posted in Alkaloids, Eguchi aza-Wittig, Methodology, Ring forming, Staudinger | Leave a Comment »

 
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