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Archive for the ‘Morita-Baylis-Hillman’ Category

Sigmatropic rearrangement

Posted by naturalproductman on May 9, 2011

Herbert Waldmann and co-workers at Max Planck have reported in Chemical Communications on an Ireland-Claisen rearrangement to access a chiral tertiary carbon center.

Ireland-Claisen

Chem Comm paper

Posted in Cascade Reactions, Ireland-Claisen, Methodology, Morita-Baylis-Hillman, Named Reactions, Pericyclic reactions, Sigmatropic Rearrangements | Leave a Comment »

Nucleophilicity: Alpha vs. Beta Position

Posted by naturalproductman on March 18, 2011

Zhi-Xiang Wang and co-workers at the Chinese Academy of Sciences have reported in JOC on a Morita Baylis Hilman type reaction using either trimethyl phosphine or an NHC catalyst.

NHC

 

JOC paper

Posted in Cascade Reactions, Computational, Conjugate Additions, Mechanistic, Methodology, Morita-Baylis-Hillman, Named Reactions, Organocatalytic | Leave a Comment »

Piperidinone Synthesis

Posted by naturalproductman on June 16, 2010

Deevi Basavaiah at the University of Hyderabad have published in Helvetica Chimica Acta on the use of Morita-Baylis-Hillman adducts as precursors to piperidinones.

baylis hillman

HCA paper

Posted in Cascade Reactions, Cobalt, Johnson Claisen rearrangement, Methodology, Morita-Baylis-Hillman, Named Reactions, Pericyclic reactions, Ring forming, Sigmatropic Rearrangements, Transition Metal | Leave a Comment »

Aza-MBH followed by IMDA

Posted by naturalproductman on May 6, 2010

Thomas Back and co-workers at the University of Calgary have recently reported in JOC on an aza-Morita-Baylis-Hillman reaction fgollowed by an intramolecular Diels-Alder reaction.

MBH

JOC paper

Posted in Cascade Reactions, Diels-Alder, Methodology, Morita-Baylis-Hillman, Named Reactions, Organocatalytic | Leave a Comment »

Hydroxysulfide Catalysts for Morita-Baylis-Hilman

Posted by naturalproductman on April 24, 2010

Javier Perez-Castells and co-workers from the Universidad San Pablo CEU in Spain have recently reported in Organic Letters on a hydroxysulfide catalyst promoted Morita-Baylis-Hilman reaction.
MBH

OL paper

Posted in Cascade Reactions, Methodology, Morita-Baylis-Hillman, Named Reactions | Leave a Comment »

Vinyl Pyridinium Ylide Cyclization

Posted by naturalproductman on April 7, 2010

Ponnusamy Shanmugam and co-workers have recently published in Organic Letters on a pyridinium ylide formation that cyclizes to form spirocyclic centers.

pyridinium

OL paper

Posted in Methodology, Morita-Baylis-Hillman, Named Reactions, Pericyclic reactions, Spirocycles, Ylides | Leave a Comment »

Asymmetric Morita-Baylis-Hillman Reaction

Posted by naturalproductman on March 30, 2010

Brian Connell and co-workers at Texas A&M have recently reported in Chemical Communications on an enantioselective Morita-Baylis-Hillman reaction using a chiral DMAP catalyst.

MBH

Chem Comm paper

Posted in Asymmetric, Iron, Methodology, Morita-Baylis-Hillman, Named Reactions, Transition Metal | Leave a Comment »

 
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