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Archive for the ‘Pauson-Khand’ Category

Ileabethoxazole synthesis

Posted by naturalproductman on June 7, 2014

David Williams and colleague have reported in JACS on the synthesis of ileabethoxazole.

JACS paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Total Synthesis | Leave a Comment »

Aza-Pauson Khand reaction

Posted by naturalproductman on August 30, 2013

Chisato Mukai and co-workers at Kanazawa University have reported in ACIE on an aza-Pauson Khand reaction.

aza

ACIE paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Transition Metal | Leave a Comment »

Merrilactone synthesis

Posted by naturalproductman on May 5, 2012

Hongbin Zhai and co-workers at the Chinese Academy of Sciences have published in ACIE on the synthesis of merrilactone where they used a Pauson-Khand reaction as one of the key steps.

Pauson-Khand

ACIE paper

Posted in Cascade Reactions, Johnson Claisen rearrangement, Methodology, Named Reactions, Neurodegenerative, Pauson-Khand, Triterpenoids | Leave a Comment »

Pauson-Khand without CO gas

Posted by naturalproductman on February 21, 2012

Tsumoru Morimoto and co-workers at NAIST (Nara Institute of Science and Technology) have reported on a rhodium catalyzed Pauson-Khand type reaction using glyceraldehyde as the CO source.

CO
Synlett paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Transition Metal | Leave a Comment »

Penostatin B synthesis

Posted by naturalproductman on December 9, 2011

Kozo Shishido and co-workers at the University of Tokushima have reported in Organic Letters on the synthesis of penostatin B relying on a relay ring closing metathesis.

penostatin

OL paper

Posted in Asymmetric, Cascade Reactions, Metathesis, Methodology, Named Reactions, Pauson-Khand, Total Synthesis | Leave a Comment »

Scalable syntheses of axinellamines

Posted by naturalproductman on August 16, 2011

Phil Baran and co-workers have reported in JACS on their scalable synthesis of axinellamines.

axinellamines

JACS paper

Posted in Alkaloids, Barbier, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Transition Metal | Leave a Comment »

Huperzine Q synthesis

Posted by naturalproductman on July 12, 2011

Hiromitsu Takayama and co-workers at Chiba University have reported in ACIEE on their synthesis of huperzine Q featuring a Pauson-Khand reaction to introduce the cyclopentenone.

huperzine

ACIEE paper

Posted in Alkaloids, Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Ring forming, Total Synthesis | Leave a Comment »

Meloscine Synthesis

Posted by naturalproductman on March 8, 2011

Chisato Mukai and colleagues have reported in Organic Letters on their synthesis of meloscine via a Pauson-Khand reaction.

meloscine

 

OL paper

Posted in Alkaloids, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Ring forming, Transition Metal | Leave a Comment »

Rhodium Catalyzed Hydroformylation

Posted by naturalproductman on January 13, 2011

I’m reminded of the Pauson-Khand reaction from this Organic Letters publication by Bernhard Breit and co-workers from FRIAS on this rhodium catalyzed hydroformylation reaction of an alkene.

rhodium

OL paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Ring forming, Transition Metal | Leave a Comment »

Rhodium Catalyzed Cycloaddition

Posted by naturalproductman on June 16, 2010

Young Keun Chung and co-workers at Seoul National University have published in ACIEE on a Pauson Khand reaction using an alcohol as the CO source and rhodium as the metal.

Pauson Khand


ACIEE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Named Reactions, Pauson-Khand, Pericyclic reactions, Rhodium, Transition Metal | Leave a Comment »

 
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