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Archive for the ‘Pauson-Khand’ Category

Aza-Pauson Khand reaction

Posted by naturalproductman on August 30, 2013

Chisato Mukai and co-workers at Kanazawa University have reported in ACIE on an aza-Pauson Khand reaction.

aza

ACIE paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Transition Metal | Leave a Comment »

Merrilactone synthesis

Posted by naturalproductman on May 5, 2012

Hongbin Zhai and co-workers at the Chinese Academy of Sciences have published in ACIE on the synthesis of merrilactone where they used a Pauson-Khand reaction as one of the key steps.

Pauson-Khand

ACIE paper

Posted in Cascade Reactions, Johnson Claisen rearrangement, Methodology, Named Reactions, Neurodegenerative, Pauson-Khand, Triterpenoids | Leave a Comment »

Pauson-Khand without CO gas

Posted by naturalproductman on February 21, 2012

Tsumoru Morimoto and co-workers at NAIST (Nara Institute of Science and Technology) have reported on a rhodium catalyzed Pauson-Khand type reaction using glyceraldehyde as the CO source.

CO
Synlett paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Transition Metal | Leave a Comment »

Penostatin B synthesis

Posted by naturalproductman on December 9, 2011

Kozo Shishido and co-workers at the University of Tokushima have reported in Organic Letters on the synthesis of penostatin B relying on a relay ring closing metathesis.

penostatin

OL paper

Posted in Asymmetric, Cascade Reactions, Metathesis, Methodology, Named Reactions, Pauson-Khand, Total Synthesis | Leave a Comment »

Scalable syntheses of axinellamines

Posted by naturalproductman on August 16, 2011

Phil Baran and co-workers have reported in JACS on their scalable synthesis of axinellamines.

axinellamines

JACS paper

Posted in Alkaloids, Barbier, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Transition Metal | Leave a Comment »

Huperzine Q synthesis

Posted by naturalproductman on July 12, 2011

Hiromitsu Takayama and co-workers at Chiba University have reported in ACIEE on their synthesis of huperzine Q featuring a Pauson-Khand reaction to introduce the cyclopentenone.

huperzine

ACIEE paper

Posted in Alkaloids, Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Ring forming, Total Synthesis | Leave a Comment »

Meloscine Synthesis

Posted by naturalproductman on March 8, 2011

Chisato Mukai and colleagues have reported in Organic Letters on their synthesis of meloscine via a Pauson-Khand reaction.

meloscine

 

OL paper

Posted in Alkaloids, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Ring forming, Transition Metal | Leave a Comment »

Rhodium Catalyzed Hydroformylation

Posted by naturalproductman on January 13, 2011

I’m reminded of the Pauson-Khand reaction from this Organic Letters publication by Bernhard Breit and co-workers from FRIAS on this rhodium catalyzed hydroformylation reaction of an alkene.

rhodium

OL paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Ring forming, Transition Metal | Leave a Comment »

Rhodium Catalyzed Cycloaddition

Posted by naturalproductman on June 16, 2010

Young Keun Chung and co-workers at Seoul National University have published in ACIEE on a Pauson Khand reaction using an alcohol as the CO source and rhodium as the metal.

Pauson Khand


ACIEE paper

Posted in Cascade Reactions, Cycloaddition, Methodology, Named Reactions, Pauson-Khand, Pericyclic reactions, Rhodium, Transition Metal | Leave a Comment »

Total Syntheses of a Few Alkaloids

Posted by naturalproductman on April 26, 2010

Chisato Mukai and co-workers from Kanazawa University have recently reported in JOC on the total syntheses of fawcettimine and lycoposperramine-B from a common tricyclic lactone intermediate.  The common precursor was synthesized from a Pauson-Khand reaction of an enyne starting material.
Pauson-Khand
JOC paper

Posted in Alkaloids, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Transition Metal | Leave a Comment »

 
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