Richard Grainger and co-workers at the University of Southampton have reported in Organic Letters on a semipinacol rearrangement of a diol promoted by triphenylphosphine.

OL paper

Oxidative Prins-pinacol

Sylvain Canesi and co-workers at Université du Québec à Montréal have reported in JOC on an oxidative Prins-pinacol approach towards platensimycin.

JOC paper

Aspergillin PZ synthesis

Larry Overman and co-workers have reported in Tetrahedron on the synthesis of aspergillin PZ using a tin mediated Prins-pinacol reaction.

Tetrahedron paper

Cinchona-alkaloid promoted cascade

Yong-Qiang Tu and co-workers at Lanzhou University have reported in Organic Letters on a cinchona alkaloid promoted halogenation/semi-Pinacol rearrangement to form beta-halo ketones asymmetrically.

JACS paper

Alopecuridine Synthesis

Yong-Qiang Tu and co-workers at Lanzhou University have reported in ACIEE on the total synthesis of alopecuridine.  The five membered ring was accessed via a SmI2 mediated pinacol coupling.

ACIEE paper

Seragakinone Synthesis

Keisuke Suzuki and co-workers at the Tokyo Institute of Technology have published in ACIEE on a synthesis of seragakinone – the key steps involve two benzoin cyclizations catalyzed by an N-heterocyclic carbene.

ACIEE paper

Asymmetric Pinacol Rearrangement

Jon Antilla and co-workers have reported in ACIEE on a Bronstead-acid catalyzed asymmetric pinacol rearrangement.

ACIEE paper

Oxidative Prins-Pinacol

Sylvain Canesi and co-workers have published in Chemistry a European Journal on an oxidative Prins-Pinacol rearrangement to access the 5,6-spirobicyclic portion of platensimycin.

Chemistry – A European Journal paper

Liphagal Synthesis

Jonathan George and co-workers at the University of Oxford have recently reported in Organic Letters on the synthesis of liphagal.  The key step to access the seven membered ring was from a Pinacol type rearrangement of the six membered ring diol using TFA.

OL paper