Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘Shi epoxidation’ Category

Shi epoxidation approach for glabrescol

Posted by naturalproductman on July 20, 2012

Jin Qu and co-workers from Nankai University have reported in Organic Letters on a synthesis of a polytetrahydrofuranyl compound using Shi epoxidation of a polyolefin intermediate.

cascade

OL paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Polyenes, Shi epoxidation, Tetrahydrofuran, Total Synthesis | Leave a Comment »

Omaezakianol Synthesis

Posted by naturalproductman on March 10, 2010

Poly-tetrahydrofuranyl compounds usually have some interesting biological activity.  Zhaoming Xiong and co-workers at Boehringer Ingelheim in Connecticut have recently published in Organic Letters on the synthesis of omaezakianol by epoxidizing a polyolefin using Shi’s catalyst followed by an acid catalyzed polyepoxide opening cascade reaction.

omaezakianol

OL paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Ring forming, Ring Opening, Shi epoxidation | Leave a Comment »

 
Follow

Get every new post delivered to your Inbox.

Join 71 other followers