Christopher Vanderwal and co-workers at UC Irvine have published in Organic Letters on a formal synthesis of porothramycin via a Zincke reaction to access the dihydropyrrolidine ring found in the natural product.

Posted by naturalproductman on June 24, 2010
Christopher Vanderwal and co-workers at UC Irvine have published in Organic Letters on a formal synthesis of porothramycin via a Zincke reaction to access the dihydropyrrolidine ring found in the natural product.

Posted in Alkaloids, Cascade Reactions, Methodology, Ring Opening, Zincke | Leave a Comment »