Naturalproductman’s Blog

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Archive for the ‘Davies lithium amide’ Category

Olefin aminohydroxylation

Posted by naturalproductman on October 19, 2011

Istvan Marko and co-workers at Université catholique de Louvain in Belgium have reported in Tetrahedron on a nice synthesis of Telaprevir using an oxaziridine and a lithium amide to functionalize an alkene.

olefin

Tetrahedron paper

Posted in Cascade Reactions, Davies lithium amide, Diseases, Hepatitis C, Methodology, Multi-Component Coupling, Named Reagents, One pot | Leave a Comment »

 
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