Dongjoo Lee and co-workers at Dankook University have reported in Tetrahedron on the synthesis of tormesol. The seven membered ring was acquired from a Horner-Wadsworth-Emmons reaction.

Posted by naturalproductman on November 21, 2011
Dongjoo Lee and co-workers at Dankook University have reported in Tetrahedron on the synthesis of tormesol. The seven membered ring was acquired from a Horner-Wadsworth-Emmons reaction.

Posted in Horner-Wadsworth-Emmons, Methodology, Named Reactions, Named Reagents, Sesquiterpenoids, Total Synthesis, Wittig | Leave a Comment »
Posted by naturalproductman on November 28, 2010
Tomasz Janecki and co-workers have published in Synlett on a nice way to make subsituted 3-methylidene-chroman-2-ones (ie: exocyclic methylenes) via 1,4-Grignard addition folowed by Wittig.

Posted in Conjugate Additions, Horner-Wadsworth-Emmons, Methodology, Named Reagents | Leave a Comment »