Kazuo Nagasawa and co-workers at Tokyo University of Agriculture and Technology have reported in Chemistry a European Journal on the synthesis of saxitoxin analogs and their biological activities towards sodium ion channels.

Posted by naturalproductman on September 18, 2011
Kazuo Nagasawa and co-workers at Tokyo University of Agriculture and Technology have reported in Chemistry a European Journal on the synthesis of saxitoxin analogs and their biological activities towards sodium ion channels.

Posted in Alkaloids, Chemical Biology, Ion channels, Methodology, Proteins, Unnatural Products | Leave a Comment »
Posted by naturalproductman on March 18, 2011
Here’s a Nature paper by Yuriy Krichok and co-workers at UCSF on the effect of progesterone onto the Ca2+ ion channel in human sperm – interestingly this response is not found in mouse sperm.
Posted in Chemical Biology, Ion channels, Proteins | Leave a Comment »