Hou-Wen Lin and co-workers at Second Military Medical University have reported in Organic Letters on the isolation of dysidavarones A-D. Dysidavarones A and B had IC50 values of 9.98 and 21.6 μM towards protein
tyrosine phosphatase 1B (PTP1B).

Posted by naturalproductman on December 2, 2011
Hou-Wen Lin and co-workers at Second Military Medical University have reported in Organic Letters on the isolation of dysidavarones A-D. Dysidavarones A and B had IC50 values of 9.98 and 21.6 μM towards protein
tyrosine phosphatase 1B (PTP1B).

Posted in Cancer, Enzymes, Protein Targets, protein tyrosine phosphatase 1B (PTP1B), Proteins, Quinones, Sesquiterpenes | Leave a Comment »
Posted by naturalproductman on September 18, 2011
Sachiko Tsukamoto and co-workers from Kumamoto University have reported in Tetrahedron Letters on the isolation of an alkaloid, spironaamidine.

Posted in Alkaloids, Quinones, Spirocycles | Leave a Comment »
Posted by naturalproductman on June 10, 2011
Rolf Muller and co-workers from Saarland University have reported in Chemistry a European Journal on the isolation of elansolid A3.

Posted in Antibiotics, Polyenes, Quinones | Leave a Comment »