Transtaganolide syntheses

Brian Stoltz and co-workers have reported in ACIE on the syntheses of transtaganolides through an Ireland-Claisen rearrangement/Diels-Alder cascade.

ACIE paper

Structural reassignment of aquatolide using DFT/NMR

Dean Tantillo and co-workers have used Gaussian in conjunction with NMR and crystallography to reassign the structure of aquatolide.

JACS paper

A 5,6,4-tricycle

Ji-Kai Liu and co-workers from the Kunming Institute of Botany have reported in Organic Letters on the isolation of trefolane.

OL paper

Chlorinated englerins

John Beutler and co-workers from the NCI have reported in the Journal of Natural Products on the isolation of chlorinated englerins and their anti-cancer activities.

JNP paper

Artemisinin chemistry

Giancarlo Marconi and co-workers have reported in Tetrahedron Letters on a reduction of artemisinin, an antimalarial compound, to break down the peroxide bond and open the ring.

TL paper

Dysidavarones

Hou-Wen Lin and co-workers at Second Military Medical University have reported in Organic Letters on the isolation of dysidavarones A-D.  Dysidavarones A and B had IC50 values of 9.98 and 21.6 μM towards protein
tyrosine phosphatase 1B (PTP1B).

OL paper

Africanan-1alpha-ol synthesis

Douglass Taber and co-workers from the University of Delaware have reported in JOC on the synthesis of trans-africanan-1alpha-ol. The synthesis of the seven membered ring was achieved from a relay-ring closing metathesis reaction.  The synthesized structure does not seem to match the reported structure.

JOC paper

Perovskone synthesis

George Majetich and co-workers at the University of Georgia have reported in Tetrahedron on the synthesis of perovskone.

Tetrahedron paper

Przewalskin B synthesis

Yong-Qiang Tu and co-workers from Lanzhou University have reported in JOC on their synthesis of przewalskin B.

JOC paper

Axisonitrile

Hunsa Prawat and co-workers from Chulabhorn Research Institute have reported in Tetrahedron on the isolation of axisonitrile.

Tetrahedron paper