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Archive for the ‘Seven-Membered Rings’ Category

Swinhoeisterol

Posted by naturalproductman on April 3, 2014

Wen Zhang and co-workers from Second Military Medical University in China have reported in Organic Letters on the isolation of swinhoeisterol.
swinhoeisterol

OL paper

Posted in Protein Targets, Seven-Membered Rings, Steroids | Leave a Comment »

Schisanwilsonene A synthesis

Posted by naturalproductman on May 10, 2013

Antonio Echavarran and co-workers at ICIQ have reported in ACIE on a synthesis of schisanwilsonene A.

seven

ACIE paper

Posted in Methodology, Sesterterpenes, Seven-Membered Rings, Total Synthesis | Leave a Comment »

Gomerone C synthesis

Posted by naturalproductman on November 16, 2012

Erick Carreira and co-worker have reported in ACIE on the synthesis of gomerone C.

gomerone C

ACIE paper

Posted in Cascade Reactions, Conia-Ene, Methodology, Named Reactions, Seven-Membered Rings, Total Synthesis | Leave a Comment »

Frondosin and liphagal via [4+3]

Posted by naturalproductman on August 13, 2012

Ying Li and co-workers from Lanzhou University have reported in Organic Letters on the synthesis of frondosin B and 5-epi-liphagal via a [4+3] cycloaddition.

4+3

OL paper

Posted in Cascade Reactions, Methodology, Seven-Membered Rings | Leave a Comment »

Lactone and allene radical cyclization

Posted by naturalproductman on July 20, 2012

David Procter and co-workers from the University of Manchester have reported in JACS on a SmI2-mediated radical cyclization of a lactone bearing an allene to form a 5,7-bicyclic ring system.

allene

JACS paper

Posted in Allenes, Methodology, Radical Chemistry, Seven-Membered Rings | Leave a Comment »

Steroid rearrangement

Posted by naturalproductman on July 9, 2012

Hans Gunther-Schmalz and colleagues have reported in Organic Letters on a BF3-promoted rearrangement of a steroid backbone.

ring

OL paper

Posted in Cascade Reactions, Mechanistic, Methodology, Ring expansion, Seven-Membered Rings | Leave a Comment »

Cationic cascade

Posted by naturalproductman on July 2, 2012

Teck Peng Loh and co-workers from the University of Science and Technology in China have reported in ACIE on a cationic cascade to access 8-oxotropanes.

cationic

ACIE paper

Posted in Cascade Reactions, Methodology, Seven-Membered Rings, Titanium, Transition Metal | Leave a Comment »

A Heck reaction for a seven membered ring

Posted by naturalproductman on June 11, 2012

Silas Cook and colleague at Indiana University have reported in Organic Letters on a formal synthesis of englerin.
englerin

OL paper

Posted in cross coupling, Heck, Methodology, Sesquiterpenoids, Seven-Membered Rings | Leave a Comment »

Friedel-Crafts cascade

Posted by naturalproductman on April 4, 2012

Arun Ghosh and co-workers from Purdue have reported in Organic Letters on a Friedel-Crafts cascade to form a seven membered ring.
seven

OL paper

Posted in Carbene, Cascade Reactions, Friedel-Crafts, Methodology, Named Reactions, Seven-Membered Rings, Titanium, Transition Metal | Leave a Comment »

Cyrneine A synthesis

Posted by naturalproductman on March 29, 2012

Karl Gademann and co-workers from the University of Basel have reported in ACIE on the synthesis of cyrneine A.  Looking at the structure – 5,6,7-tricycle – I’d say that Nature knows how to count.
cyrneine A

ACIE paper

Posted in Methodology, Seven-Membered Rings, Total Synthesis | Leave a Comment »

 
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