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Archive for the ‘Spiroketals’ Category

Griseusin B progress

Posted by naturalproductman on April 18, 2013

Margaret Brimble and colleague have reported in Org Lett on their strategy for griseusin B.

griseusin B

OL paper

Posted in Methodology, Spiroketals | Leave a Comment »

Spirangien A synthesis

Posted by naturalproductman on January 17, 2013

Mark Rizzacasa and co-workers from the University of Melbourne have reported in Organic Letters on their formal synthesis of spirangien A.

spirangien A

OL paper

Posted in Iron, Manganese, Metathesis, Methodology, Polyketides, Spiroketals, Transition Metal | Leave a Comment »

Acortatarins A and B syntheses

Posted by naturalproductman on August 31, 2012

Derek Tan and co-workers at Sloan Kettering have reported in Organic Letters on their syntheses of acortatarins A and B.

acortatarins A and B

OL paper

Posted in Alkaloids, Methodology, Polyketides, Spiroketals, Total Synthesis | Leave a Comment »

Caloundrin B synthesis

Posted by naturalproductman on February 29, 2012

Dale Ward and colleague at the University of Sasketchewan have reported in Organic Letters on the synthesis of

caloundrin B

OL paper

Posted in Cascade Reactions, Methodology, Polyketides, Spiroketals | Leave a Comment »

Danshenspiroketallactone synthesis

Posted by naturalproductman on January 7, 2012

Margaret Brimble and co-workers have reported in Synlett on the synthesis of danshenspiroketallactone.
spiroketal

Synlett paper

Posted in Cascade Reactions, Methodology, Radical Chemistry, Spiroketals | Leave a Comment »

Acortatarins syntheses

Posted by naturalproductman on September 30, 2011

Gangarajula Sudhakar and co-workers at IICT have reported in Organic Letters on the synthesis of acortatarins.

acortatarins

OL paper

Posted in Alkaloids, Asymmetric, Cascade Reactions, Methodology, Spirocycles, Spiroketals, Total Synthesis | Leave a Comment »

Ring rearrangement metathesis

Posted by naturalproductman on August 29, 2011

Nicolas Blanchard and co-workers at Universite de Haute-Alsace in France have reported in Chem Comm on  a spiroketalization via a ring rearrangement metathesis – add that to your new lexicon.

metathesis

Chem Comm paper

Posted in Cascade Reactions, Metathesis, Methodology, Ring forming, Ring Opening, Ruthenium, Spirocyclic centers, Spiroketals, Transition Metal | Leave a Comment »

Spongiastatin and derivatives

Posted by naturalproductman on August 12, 2011

Amos Smith and co-workers have reported in JACS on the synthesis and the biological evaluation of spongiastatin derivatives.

spongiastatin

JACS paper

Posted in Chemical Biology, Methodology, Polyketides, Spiroketals, Total Synthesis | Leave a Comment »

Dinophysistoxin-2 synthesis

Posted by naturalproductman on July 3, 2011

Craig Forsyth and co-workers from Ohio State University have reported in ACIEE on their synthesis of dinophysistoxin-2.

spiroketal

ACIEE paper

Posted in Chemical Biology, Methodology, Spiroketals, Total Synthesis | Leave a Comment »

Intramolecular epoxide opening

Posted by naturalproductman on May 4, 2011

Derek Tan and co-workers at Sloan Kettering have reported in JACS on an intramolecular epoxide opening to form spiroketals.

spiroketal

JACS paper

Posted in Cascade Reactions, Methodology, Spiroketals | Leave a Comment »

 
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